Chondroitin sulfate-based biomaterials for tissue engineering
DC Field | Value | Language |
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dc.contributor.author | Kwon, Hyuck Joon | - |
dc.contributor.author | Han, Youngbae | - |
dc.date.available | 2020-07-10T06:41:41Z | - |
dc.date.created | 2020-07-06 | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1300-0152 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hongik/handle/2020.sw.hongik/8820 | - |
dc.description.abstract | Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) that is usually found attached to proteins as part of a proteoglycan. The use of CS-based biomaterials in the field of tissue engineering applications has been intensively growing over the past decades because CS is a biopolymer with the major advantages of being biodegradable, biocompatible, easily available, and highly versatile. In vitro and in vivo studies have shown that CS-based biomaterials upregulate cartilage-specific gene expression in chondrocytes and mesenchymal stem cells and also support osteogenic differentiation by increasing the effectiveness of bone anabolic growth factors. Chondroitin sulfate proteoglycan plays a key role during the acute recovery stage after spinal cord injury by activating microglia/macrophages and modulating neurotrophic factor secretion. In addition, CS-based materials promote the wound-healing process and stimulate the regeneration of skin defects. Moreover, CS can be used to construct high toughness gels by having a double network structure. Taken together, CS-based biomaterials would be a useful material for successful replacement and regeneration of damaged cartilage, bone, skin, and neural tissues. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY | - |
dc.subject | INTERPENETRATING POLYMER NETWORK | - |
dc.subject | GROWTH-FACTOR | - |
dc.subject | EXTRACELLULAR-MATRIX | - |
dc.subject | STEM-CELLS | - |
dc.subject | ARTIFICIAL SKIN | - |
dc.subject | BURN INJURY | - |
dc.subject | CARTILAGE | - |
dc.subject | SCAFFOLD | - |
dc.subject | REGENERATION | - |
dc.subject | HYDROGELS | - |
dc.title | Chondroitin sulfate-based biomaterials for tissue engineering | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Han, Youngbae | - |
dc.identifier.doi | 10.3906/biy-1507-16 | - |
dc.identifier.scopusid | 2-s2.0-84976508405 | - |
dc.identifier.wosid | 000370808100003 | - |
dc.identifier.bibliographicCitation | TURKISH JOURNAL OF BIOLOGY, v.40, no.2, pp.290 - 299 | - |
dc.relation.isPartOf | TURKISH JOURNAL OF BIOLOGY | - |
dc.citation.title | TURKISH JOURNAL OF BIOLOGY | - |
dc.citation.volume | 40 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 290 | - |
dc.citation.endPage | 299 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Life Sciences & Biomedicine - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Biology | - |
dc.subject.keywordPlus | INTERPENETRATING POLYMER NETWORK | - |
dc.subject.keywordPlus | GROWTH-FACTOR | - |
dc.subject.keywordPlus | EXTRACELLULAR-MATRIX | - |
dc.subject.keywordPlus | STEM-CELLS | - |
dc.subject.keywordPlus | ARTIFICIAL SKIN | - |
dc.subject.keywordPlus | BURN INJURY | - |
dc.subject.keywordPlus | CARTILAGE | - |
dc.subject.keywordPlus | SCAFFOLD | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | HYDROGELS | - |
dc.subject.keywordAuthor | Chondroitin sulfate | - |
dc.subject.keywordAuthor | tissue engineering | - |
dc.subject.keywordAuthor | regenerative medicine | - |
dc.subject.keywordAuthor | scaffold | - |
dc.subject.keywordAuthor | stem cell | - |
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