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Deciphering signaling pathways in hematopoietic stem cells: the molecular complexity of Myelodysplastic Syndromes (MDS) and leukemic progression

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dc.contributor.authorCasalin, Irene-
dc.contributor.authorDe Stefano, Alessia-
dc.contributor.authorCeneri, Eleonora-
dc.contributor.authorCappellini, Alessandra-
dc.contributor.authorFinelli, Carlo-
dc.contributor.authorCurti, Antonio-
dc.contributor.authorPaolini, Stefania-
dc.contributor.authorParisi, Sarah-
dc.contributor.authorZannoni, Letizia-
dc.contributor.authorBoultwood, Jacqueline-
dc.contributor.authorMcCubrey, James A.-
dc.contributor.authorSuh, Pann-Ghill-
dc.contributor.authorRamazzotti, Giulia-
dc.contributor.authorFiume, Roberta-
dc.contributor.authorRatti, Stefano-
dc.contributor.authorManzoli, Lucia-
dc.contributor.authorCocco, Lucio-
dc.contributor.authorFollo, Matilde Y.-
dc.date.accessioned2024-05-20T08:30:11Z-
dc.date.available2024-05-20T08:30:11Z-
dc.date.issued2024-01-
dc.identifier.issn2212-4926-
dc.identifier.issn2212-4934-
dc.identifier.urihttp://scholarworks.bwise.kr/kbri/handle/2023.sw.kbri/1175-
dc.description.abstractMyelodysplastic Syndromes, a heterogeneous group of hematological disorders, are characterized by abnormalities in phosphoinositide-dependent signaling, epigenetic regulators, apoptosis, and cytokine interactions within the bone marrow microenvironment, contributing to disease pathogenesis and neoplastic growth. Comprehensive knowledge of these pathways is crucial for the development of innovative therapies that aim to restore normal apoptosis and improve patient outcomes.-
dc.language영어-
dc.language.isoENG-
dc.publisherElsevier Ltd-
dc.titleDeciphering signaling pathways in hematopoietic stem cells: the molecular complexity of Myelodysplastic Syndromes (MDS) and leukemic progression-
dc.typeArticle-
dc.publisher.location네델란드-
dc.identifier.doi10.1016/j.jbior.2024.101014-
dc.identifier.scopusid2-s2.0-85183176429-
dc.identifier.wosid001202864900001-
dc.identifier.bibliographicCitationAdvances in Biological Regulation, v.91-
dc.citation.titleAdvances in Biological Regulation-
dc.citation.volume91-
dc.type.docTypeArticle-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.subject.keywordAuthorMyelodysplastic Syndromes-
dc.subject.keywordAuthorAcute myeloid leukemia-
dc.subject.keywordAuthorPhosphoinositide signaling-
dc.subject.keywordAuthorEpigenetic regulation-
dc.subject.keywordAuthorCytokines secretion-
dc.subject.keywordAuthorApoptosis-
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