Mathematical analysis of the effects of valvular regurgitation on the pumping efficacy of continuous and pulsatile left ventricular assist devices
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yoo Seok | - |
dc.contributor.author | Kim, Eun-Hye | - |
dc.contributor.author | Kim, Hyeong-Gyun | - |
dc.contributor.author | Shim, Eun Bo | - |
dc.contributor.author | Song, Kwang-Soup | - |
dc.contributor.author | Lim, Ki Moo | - |
dc.date.available | 2021-04-29T08:42:47Z | - |
dc.date.created | 2020-06-16 | - |
dc.date.issued | 2016-03 | - |
dc.identifier.issn | 2213-4220 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/kumoh/handle/2020.sw.kumoh/19151 | - |
dc.description.abstract | Background: A left ventricular assist device (LVAD) is normally contraindicated in significant aortic regurgitation (AR) and requires intraoperative valve repair or exclusion. Nevertheless, AR can coexist with an LVAD, so a valid question when asked might still be of clinical significance. The purpose of this study is to analyze the effects of valve regurgitation on the pumping efficacy of continuous and pulsatile LVADs with a computational method. Methods: A cardiovascular model was developed based on the Windkessel model, which reflects the hemodynamic flow resistance and the blood wall elasticity. Using the Windkessel model, important cardiovascular components, such as the right atrium, right ventricle, pulmonary artery, pulmonary vein, left atrium (LA), left ventricle (LV), aorta, and branching blood vessels, were expressed. Results: In the case of AR, continuous and pulsatile LVADs improved cardiac output and reduced mechanical load slightly. In the case of mitral regurgitation, the LVADs improved cardiac output (cardiac outputs were about 5 L/min regardless of the severity of regurgitation) and reduced afterload significantly. Conclusion: AR reduced both continuous and pulsatile LVAD function significantly while mitral regurgitation did not affect their pumping efficacy. (C) 2016 Korea Institute of Oriental Medicine. Published by Elsevier. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | CONGESTIVE-HEART-FAILURE | - |
dc.subject | ELECTROMECHANICS MODEL | - |
dc.subject | COMPUTATIONAL ANALYSIS | - |
dc.subject | INTRAVENOUS MILRINONE | - |
dc.subject | AORTIC REGURGITATION | - |
dc.subject | MITRAL REGURGITATION | - |
dc.subject | SUPPORT | - |
dc.subject | MANAGEMENT | - |
dc.subject | THERAPY | - |
dc.subject | BRIDGE | - |
dc.title | Mathematical analysis of the effects of valvular regurgitation on the pumping efficacy of continuous and pulsatile left ventricular assist devices | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Kwang-Soup | - |
dc.contributor.affiliatedAuthor | Lim, Ki Moo | - |
dc.identifier.doi | 10.1016/j.imr.2016.01.001 | - |
dc.identifier.wosid | 000379243800004 | - |
dc.identifier.bibliographicCitation | INTEGRATIVE MEDICINE RESEARCH, v.5, no.1, pp.22 - 29 | - |
dc.relation.isPartOf | INTEGRATIVE MEDICINE RESEARCH | - |
dc.citation.title | INTEGRATIVE MEDICINE RESEARCH | - |
dc.citation.volume | 5 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 22 | - |
dc.citation.endPage | 29 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002093222 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
dc.relation.journalResearchArea | Integrative & Complementary Medicine | - |
dc.relation.journalWebOfScienceCategory | Integrative & Complementary Medicine | - |
dc.subject.keywordPlus | CONGESTIVE-HEART-FAILURE | - |
dc.subject.keywordPlus | ELECTROMECHANICS MODEL | - |
dc.subject.keywordPlus | COMPUTATIONAL ANALYSIS | - |
dc.subject.keywordPlus | INTRAVENOUS MILRINONE | - |
dc.subject.keywordPlus | AORTIC REGURGITATION | - |
dc.subject.keywordPlus | MITRAL REGURGITATION | - |
dc.subject.keywordPlus | SUPPORT | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | BRIDGE | - |
dc.subject.keywordAuthor | aortic regurgitation | - |
dc.subject.keywordAuthor | left ventricular assist device | - |
dc.subject.keywordAuthor | mitral regurgitation | - |
dc.subject.keywordAuthor | regurgitation severity | - |
dc.subject.keywordAuthor | Windkessel model | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
350-27, Gumi-daero, Gumi-si, Gyeongsangbuk-do, Republic of Korea (39253)054-478-7170
COPYRIGHT 2020 Kumoh University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.