Needle-Like Multifunctional Biphasic Microfiber for Minimally Invasive Implantable Bioelectronics
DC Field | Value | Language |
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dc.contributor.author | Nam, Seonghyeon | - |
dc.contributor.author | Cha, Gi Doo | - |
dc.contributor.author | Sunwoo, Sung-Hyuk | - |
dc.contributor.author | Jeong, Jae Hwan | - |
dc.contributor.author | Kang, Hyejeong | - |
dc.contributor.author | Park, Ok Kyu | - |
dc.contributor.author | Lee, Kyeong-Yeon | - |
dc.contributor.author | Oh, Seil | - |
dc.contributor.author | Hyeon, Taeghwan | - |
dc.contributor.author | Choi, Seung Hong | - |
dc.contributor.author | Lee, Seung-Pyo | - |
dc.contributor.author | Kim, Dae-Hyeong | - |
dc.date.accessioned | 2024-07-19T08:30:28Z | - |
dc.date.available | 2024-07-19T08:30:28Z | - |
dc.date.issued | 2024-06 | - |
dc.identifier.issn | 0935-9648 | - |
dc.identifier.issn | 1521-4095 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/kumoh/handle/2020.sw.kumoh/28811 | - |
dc.description.abstract | Implantable bioelectronics has attracted significant attention in electroceuticals and clinical medicine for precise diagnosis and efficient treatment of target diseases. However, conventional rigid implantable devices face challenges such as poor tissue-device interface and unavoidable tissue damage during surgical implantation. Despite continuous efforts to utilize various soft materials to address such issues, their practical applications remain limited. Here, a needle-like stretchable microfiber composed of a phase-convertible liquid metal (LM) core and a multifunctional nanocomposite shell for minimally invasive soft bioelectronics is reported. The sharp tapered microfiber can be stiffened by freezing akin to a conventional needle to penetrate soft tissue with minimal incision. Once implanted in vivo where the LM melts, unlike conventional stiff needles, it regains soft mechanical properties, which facilitate a seamless tissue-device interface. The nanocomposite incorporating with functional nanomaterials exhibits both low impedance and the ability to detect physiological pH, providing biosensing and stimulation capabilities. The fluidic LM embedded in the nanocomposite shell enables high stretchability and strain-insensitive electrical properties. This multifunctional biphasic microfiber conforms to the surfaces of the stomach, muscle, and heart, offering a promising approach for electrophysiological recording, pH sensing, electrical stimulation, and radiofrequency ablation in vivo. The needle-like stretchable multifunctional microfiber for minimally invasive bioelectronics is developed, featuring a liquid metal core-nanocomposite shell structure. This design allows stiffness control based on phase transition and offers advantageous properties of both materials such as softness, stretchability, conductivity, and strain-insensitivity. Further functionalization enhances its biosensing and stimulation capabilities, showing promise for clinical translation across various in vivo applications. image | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Needle-Like Multifunctional Biphasic Microfiber for Minimally Invasive Implantable Bioelectronics | - |
dc.type | Article | - |
dc.publisher.location | 독일 | - |
dc.identifier.doi | 10.1002/adma.202404101 | - |
dc.identifier.scopusid | 2-s2.0-85195886018 | - |
dc.identifier.wosid | 001246097000001 | - |
dc.identifier.bibliographicCitation | ADVANCED MATERIALS | - |
dc.citation.title | ADVANCED MATERIALS | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.subject.keywordPlus | ELECTRONICS | - |
dc.subject.keywordPlus | DURATION | - |
dc.subject.keywordPlus | SOFT | - |
dc.subject.keywordAuthor | bioelectronics | - |
dc.subject.keywordAuthor | cardiac application | - |
dc.subject.keywordAuthor | implantable device | - |
dc.subject.keywordAuthor | in vivo application | - |
dc.subject.keywordAuthor | liquid metal | - |
dc.subject.keywordAuthor | minimally invasive | - |
dc.subject.keywordAuthor | nanocomposite | - |
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