Clinical Features of Drug-induced Liver Injury According to Etiology
DC Field | Value | Language |
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dc.contributor.author | Lee, Byoung Moo | - |
dc.contributor.author | Lee, Woong Cheul | - |
dc.contributor.author | Jang, Jae Young | - |
dc.contributor.author | Ahn, Pyoung | - |
dc.contributor.author | Kim, Jin Nyoung | - |
dc.contributor.author | Jeong, Soung Won | - |
dc.contributor.author | Park, Eui Ju | - |
dc.contributor.author | Lee, Sae Hwan | - |
dc.contributor.author | Kim, Sang Gyune | - |
dc.contributor.author | Cha, Sang-Woo | - |
dc.contributor.author | Kim, Young Seok | - |
dc.contributor.author | Cho, Young Deok | - |
dc.contributor.author | Kim, Hong Soo | - |
dc.contributor.author | Kim, Boo Sung | - |
dc.date.accessioned | 2021-08-11T19:24:44Z | - |
dc.date.available | 2021-08-11T19:24:44Z | - |
dc.date.issued | 2015-12 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10069 | - |
dc.description.abstract | Drug-induced liver injury (DILI) is an increasingly common cause of acute hepatitis. We examined clinical features and types of liver injury of 65 affected patients who underwent liver biopsy according DILI etiology. The major causes of DILI were the use of herbal medications (43.2%), prescribed medications (21.6%), and traditional therapeutic preparations and dietary supplements (35%). DILI from herbal medications, traditional therapeutic preparations, and dietary supplements was associated with higher elevations in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels than was DILI from prescription medications. The types of liver injury based on the R ratio were hepatocellular (67.7%), mixed (10.8%), and cholestatic (21.5%). Herbal medications and traditional therapeutic preparations were more commonly associated with hepatocellular liver injury than were prescription medications (P = 0.002). Herbal medications and traditional therapeutic preparations induce more hepatocellular DILI and increased elevations in AST and ALT than prescribed medications. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한의학회 | - |
dc.title | Clinical Features of Drug-induced Liver Injury According to Etiology | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3346/jkms.2015.30.12.1815 | - |
dc.identifier.scopusid | 2-s2.0-84951839141 | - |
dc.identifier.wosid | 000368136400015 | - |
dc.identifier.bibliographicCitation | Journal of Korean Medical Science, v.30, no.12, pp 1815 - 1820 | - |
dc.citation.title | Journal of Korean Medical Science | - |
dc.citation.volume | 30 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1815 | - |
dc.citation.endPage | 1820 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002055470 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordAuthor | Drug-induced Liver Injury | - |
dc.subject.keywordAuthor | Hepatotoxicity | - |
dc.subject.keywordAuthor | Etiology | - |
dc.subject.keywordAuthor | Plants, Medicinal | - |
dc.subject.keywordAuthor | Traditional Therapy | - |
dc.subject.keywordAuthor | Prescribed Medicines | - |
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