Late paradoxical lymph node enlargement during and after anti-tuberculosis treatment in non-HIV-infected patients
DC Field | Value | Language |
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dc.contributor.author | Yu, S. N. | - |
dc.contributor.author | Cho, O-H. | - |
dc.contributor.author | Park, K-H. | - |
dc.contributor.author | Jung, J. | - |
dc.contributor.author | Kim, Y. K. | - |
dc.contributor.author | Lee, J. Y. | - |
dc.contributor.author | Chong, Y-P. | - |
dc.contributor.author | Lee, S-O. | - |
dc.contributor.author | Choi, S-H. | - |
dc.contributor.author | Kim, Y. S. | - |
dc.contributor.author | Woo, J. H. | - |
dc.contributor.author | Kim, S-H. | - |
dc.date.accessioned | 2021-08-11T19:25:53Z | - |
dc.date.available | 2021-08-11T19:25:53Z | - |
dc.date.issued | 2015-11 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.issn | 1815-7920 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10169 | - |
dc.description.abstract | SETTINGS: A tertiary referral centre in South Korea. OBJECTIVE: To investigate the incidence, clinical characteristics and outcomes of late paradoxical response (>4 months after the initiation of anti-tuberculosis treatment) during and after anti-tuberculosis treatment in non-human immunodeficiency virus (HIV) infected patients with lymph node tuberculosis (TB). DESIGN: We retrospectively reviewed the medical records of non-HIV-infected patients with lymph node TB between 1997 and 2007, and prospectively enrolled patients with newly diagnosed lymph node TB between 2008 and 2013. RESULTS: Of 467 patients with confirmed and probable lymph node TB, 83 (18%) displayed a paradoxical response: 57 of these (69%) were classified as early and 26 (31%) as late paradoxical response. Patients with late paradoxical response (median 12 months) received more prolonged anti-tuberculosis treatment than those with early (median 9 months, P < 0.001) or no paradoxical response (median 9 months, P < 0.001). The frequency of post-treatment lymph node enlargement increased progressively from those without any paradoxical response (6%), through those with an early response (12%) to those with a late response (23%). CONCLUSIONS: Paradoxical response presents late in about one third of non-HIV-infected patients with lymph node TB who experience a response. Although anti-tuberculosis treatment is commonly prolonged in patients with late paradoxical response, post-treatment lymph node enlargement is more frequent in these patients. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | International Union Against Tuberculosis And Lung Disease/Union Internationale Contre la Tuberculose et les Maladies Respiratories | - |
dc.title | Late paradoxical lymph node enlargement during and after anti-tuberculosis treatment in non-HIV-infected patients | - |
dc.type | Article | - |
dc.publisher.location | 프랑스 | - |
dc.identifier.doi | 10.5588/ijtld.15.0257 | - |
dc.identifier.scopusid | 2-s2.0-84945583641 | - |
dc.identifier.wosid | 000364270200019 | - |
dc.identifier.bibliographicCitation | International Journal of Tuberculosis and Lung Disease, v.19, no.11, pp 1388 - 1394 | - |
dc.citation.title | International Journal of Tuberculosis and Lung Disease | - |
dc.citation.volume | 19 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1388 | - |
dc.citation.endPage | 1394 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | TUBERCULOSIS | - |
dc.subject.keywordAuthor | tuberculosis | - |
dc.subject.keywordAuthor | lymphadenopathy | - |
dc.subject.keywordAuthor | paradoxical response | - |
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