Eupartoium makinoi suppresses lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression
DC Field | Value | Language |
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dc.contributor.author | Ahn, Sang-Il | - |
dc.contributor.author | Lim, Se Jin | - |
dc.contributor.author | Gu, Gyo-Jeong | - |
dc.contributor.author | Kim, Ji-Soo | - |
dc.contributor.author | Paek, Ji Hun | - |
dc.contributor.author | Kim, Songmun | - |
dc.contributor.author | Lim, Soon Sung | - |
dc.contributor.author | Youn, Hyung-Sun | - |
dc.date.accessioned | 2021-08-11T19:46:21Z | - |
dc.date.available | 2021-08-11T19:46:21Z | - |
dc.date.issued | 2015-07-04 | - |
dc.identifier.issn | 0954-0105 | - |
dc.identifier.issn | 1465-3443 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10464 | - |
dc.description.abstract | Inflammation is involved in numerous diseases including cancer. Inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) play important roles in the development of certain inflammatory diseases. Eupatorium makinoi, which belongs to a family of Asteraceae plants, is used medicinally in East Asia. We investigated the effects of an ethanol extract of E. makinoi (EEM) on nuclear factor-kappa B (NF-kappa B) activation and the expression of iNOS and COX-2 with lipopolysaccharide (TLR4 agonist) in murine macrophages. EEM suppressed NF-kappa B activation and iNOS and COX-2 expression induced by LPS. These results suggest that EEM may regulate TLR4 signalling pathways and this may be a useful strategy for anti-inflammatory therapies. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Taylor & Francis | - |
dc.title | Eupartoium makinoi suppresses lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1080/09540105.2014.968768 | - |
dc.identifier.scopusid | 2-s2.0-84926522795 | - |
dc.identifier.wosid | 000351911800003 | - |
dc.identifier.bibliographicCitation | Food and Agricultural Immunology, v.26, no.4, pp 496 - 503 | - |
dc.citation.title | Food and Agricultural Immunology | - |
dc.citation.volume | 26 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 496 | - |
dc.citation.endPage | 503 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.subject.keywordPlus | TOLL-LIKE RECEPTORS | - |
dc.subject.keywordPlus | INFLAMMATORY CELLS | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | TBK1 | - |
dc.subject.keywordAuthor | Eupatorium makinoi | - |
dc.subject.keywordAuthor | cyclooxygenase-2 | - |
dc.subject.keywordAuthor | lipopolysaccharide | - |
dc.subject.keywordAuthor | inducible nitric oxide synthase | - |
dc.subject.keywordAuthor | nuclear factor-kappa B | - |
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