Predictors of malignancy in pure branch duct type intraductal papillary mucinous neoplasm of the pancreas: A nationwide multicenter study
DC Field | Value | Language |
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dc.contributor.author | Kim, Tae Hyeon | - |
dc.contributor.author | Song, Tae Jun | - |
dc.contributor.author | Hwang, Jin-hyeok | - |
dc.contributor.author | Yoo, Kyo-sang | - |
dc.contributor.author | Lee, Woo-jin | - |
dc.contributor.author | Lee, Kwang-hyuck | - |
dc.contributor.author | Dong, Seok-ho | - |
dc.contributor.author | Park, Chang-hwan | - |
dc.contributor.author | Park, Eun-taek | - |
dc.contributor.author | Moon, Jong-ho | - |
dc.contributor.author | Kim, Ho-gak | - |
dc.contributor.author | Kim, Eun-young | - |
dc.contributor.author | Cho, Kwang Bum | - |
dc.contributor.author | Kim, Hong-ja | - |
dc.contributor.author | Lee, Seung-ok | - |
dc.contributor.author | Cheon, Young Koog | - |
dc.contributor.author | Lee, Jeong Mi | - |
dc.contributor.author | Oh, Dong Wook | - |
dc.contributor.author | Kim, Myung-Hwan | - |
dc.date.accessioned | 2021-08-11T19:46:52Z | - |
dc.date.available | 2021-08-11T19:46:52Z | - |
dc.date.issued | 2015-07 | - |
dc.identifier.issn | 1424-3903 | - |
dc.identifier.issn | 1424-3911 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10521 | - |
dc.description.abstract | Background/Objectives: Prediction of malignancy in patients with BD-IPMNs is critical for the management. The aim of this study was to elucidate predictors of malignancy in patients with 'pure' BD-IPMNs who had a main pancreatic duct (MPD) diameter of <= 5 mm according to the most recent international consensus criteria and in whom MPD involvement was excluded on postoperative histology. Methods: We identified 177 patients with 'pure' BD-IPMNs based on preoperative imaging and postoperative histology from 15 tertiary referral centers in Korea. BD-IPMNs with low-grade (n = 72) and moderate-grade (n = 66) dysplasia were grouped as benign and BD-IPMNs with high-grade dysplasia (n = 10) and invasive carcinoma (n = 29) were grouped as malignancy. Results: On univariate analysis, particular symptoms (jaundice and clinical pancreatitis), CT findings (cyst size > 3 cm, the presence of enhancing mural nodules) and EUS features (the presence of mural nodules, the mural nodule size > 5 mm) were significant risk factors predicting malignant BD-IPMNs. Multivariate analysis revealed that the cyst size > 3 cm (odds ratio = 9.9), the presence of enhancing mural nodules on CT (odds ratio = 19.3) and the mural nodule size > 5 mm on EUS (odds ratio = 14.9) were the independent risk factors for the presence of malignancy in BD-IPMNs (p < 0.001). Conclusions: The cyst size > 3 cm, the presence of enhancing mural nodules on Cl, the mural nodule size > 5 mm on EUS are three independent predictors of malignancy in patients with 'pure' BD-IPMNs. Copyright (C) 2015, IAP and EPC. Published by Elsevier India, a division of Reed Elsevier India Pvt. Ltd. All rights reserved. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | S. Karger AG | - |
dc.title | Predictors of malignancy in pure branch duct type intraductal papillary mucinous neoplasm of the pancreas: A nationwide multicenter study | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.pan.2015.04.010 | - |
dc.identifier.wosid | 000359327800016 | - |
dc.identifier.bibliographicCitation | Pancreatology, v.15, no.4, pp 405 - 410 | - |
dc.citation.title | Pancreatology | - |
dc.citation.volume | 15 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 405 | - |
dc.citation.endPage | 410 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | INTERNATIONAL-CONSENSUS-GUIDELINES | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | CYSTIC NEOPLASMS | - |
dc.subject.keywordPlus | IMAGING FEATURES | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | CONCOMITANT | - |
dc.subject.keywordPlus | SIZE | - |
dc.subject.keywordPlus | ADENOCARCINOMAS | - |
dc.subject.keywordPlus | ULTRASONOGRAPHY | - |
dc.subject.keywordPlus | TRANSFORMATION | - |
dc.subject.keywordAuthor | Branch duct type intraductal papillary mucinous neoplasm | - |
dc.subject.keywordAuthor | Malignancy | - |
dc.subject.keywordAuthor | Endoscopic ultrasonography | - |
dc.subject.keywordAuthor | Multicenter study | - |
dc.subject.keywordAuthor | Risk factors | - |
dc.subject.keywordAuthor | Pancreas | - |
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