Statin eligibility and cardiovascular risk burden assessed by coronary artery calcium score: Comparing the two guidelines in a large Korean cohort
DC Field | Value | Language |
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dc.contributor.author | Rhee, Eun-Jung | - |
dc.contributor.author | Park, Se Eun | - |
dc.contributor.author | Oh, Hyung Geun | - |
dc.contributor.author | Park, Cheol-Young | - |
dc.contributor.author | Oh, Ki-Won | - |
dc.contributor.author | Park, Sung-Woo | - |
dc.contributor.author | Blankstein, Ron | - |
dc.contributor.author | Plutzky, Jorge | - |
dc.contributor.author | Lee, Won-Young | - |
dc.date.accessioned | 2021-08-11T20:25:29Z | - |
dc.date.available | 2021-08-11T20:25:29Z | - |
dc.date.issued | 2015-05 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.issn | 1879-1484 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10701 | - |
dc.description.abstract | Objective: To investigate the statin eligibility and the predictabilities for cardiovascular disease between AHA/ACC and ATPIII guidelines, comparing those results to concomitant coronary artery calcium scores (CACS) in a large cohort of Korean individuals who met statin-eligibility criteria. Methods: Among 19,920 participants in a health screening program, eligibility for statin treatment was assessed by the two guidelines. The presence and extent of coronary artery calcification (CAC) was measured by multi-detector computed tomography and compared among the various groups defined by the two guidelines. Results: Applying the new ACC/AHA guideline to the health screening cohort increased the statin-eligible population from 18.7% (as defined by ATP III) to 21.7%. Statin-eligible subjects as defined only by ACC/AHA guideline manifested a higher proportion of subjects with CAC compared with those meeting only ATP-III criteria even after adjustment for age and sex (47.1 vs. 33.8%, p < 0.01). Statin-eligible subjects as defined by ACC/AHA guideline showed higher odds ratio for the presence of CACS > 0 compared with those meeting ATP-III criteria {3.493 (3.245 similar to 3.759) vs. 2.865 (2.653 similar to 3.094)}, which was attenuated after adjusted for age and sex. Conclusions: In this large Korean cohort, more subjects would have qualified for statin initiation under the new ACC/AHA guideline as compared with the proportion recommended for statin treatment by ATP III guideline. Among statin-eligible Korean health screening subjects, the new ACC/AHA guideline identified a greater extent of atherosclerosis as assessed by CACS as compared to ATP III guideline assessment. (C) 2015 Elsevier Ireland Ltd. All rights reserved. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | Statin eligibility and cardiovascular risk burden assessed by coronary artery calcium score: Comparing the two guidelines in a large Korean cohort | - |
dc.type | Article | - |
dc.publisher.location | 아일랜드 | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2015.03.006 | - |
dc.identifier.scopusid | 2-s2.0-84925349083 | - |
dc.identifier.wosid | 000352703400038 | - |
dc.identifier.bibliographicCitation | Atherosclerosis, v.240, no.1, pp 242 - 249 | - |
dc.citation.title | Atherosclerosis | - |
dc.citation.volume | 240 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 242 | - |
dc.citation.endPage | 249 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | BEAM COMPUTED-TOMOGRAPHY | - |
dc.subject.keywordPlus | ACC/AHA GUIDELINES | - |
dc.subject.keywordPlus | HEART-DISEASE | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | AMERICAN | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | EVENTS | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | Atherosclerosis | - |
dc.subject.keywordAuthor | Coronary artery calcification (CAC) | - |
dc.subject.keywordAuthor | Statin | - |
dc.subject.keywordAuthor | Pooled Cohort Equation | - |
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