Increased Risk for Intracranial Arterial Stenosis in Subjects With Coronary Artery Calcification
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh, Hyung-Geun | - |
dc.contributor.author | Chung, Pil-Wook | - |
dc.contributor.author | Rhee, Eun-Jung | - |
dc.date.accessioned | 2021-08-11T20:46:29Z | - |
dc.date.available | 2021-08-11T20:46:29Z | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 0039-2499 | - |
dc.identifier.issn | 1524-4628 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10990 | - |
dc.description.abstract | Background and Purpose-Intracranial arterial stenosis (ICAS) is considered an important cause of stroke in Asians. Coronary artery calcification (CAC) is a surrogate marker for subclinical atherosclerosis. We aimed to analyze the association of ICAS assessed by transcranial Doppler ultrasonography and CAC in middle-aged Korean population. Methods-This study included 10 550 participants (81.3% men, mean age 43 years) from a health screening program, in whom transcranial Doppler ultrasonography was used to detect >50% intracranial stenosis based on criteria modified from the stroke outcomes and neuroimaging of intracranial atherosclerosis trial. Multidetector computed tomography was used to assess coronary artery calcium score (CACS). CAC grade (0, 1-100, and >100) was defined by CACS. Results-The subjects with CAC showed significantly higher proportion of subjects with ICAS compared with those without CAC (4.4% versus 2.8%; P<0.01). Conversely, the subjects with ICAS showed significantly higher proportion of subjects with CAC (24.8% versus 17.1%; P<0.01). When logistic regression analysis was performed with ICAS as the dependent variable, the presence of CAC showed significantly increased risk for ICAS after adjustment for confounding variables (odds ratio, 1.439; 95% confidence interval, 1.095-1.891). When CACS grade was included in the model, the odds ratio for ICAS was the highest in subjects with CACS >400 compared with those with CACS=0 (odds ratio, 2.754; 95% confidence interval, 1.205-2.936). Conclusions-The risk for ICAS was significantly increased in middle-aged Korean subjects with CAC compared with that in those without CAC. These findings suggest the possibility of a separate undetected atherosclerotic focus in subjects with 1 atherosclerotic event. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Increased Risk for Intracranial Arterial Stenosis in Subjects With Coronary Artery Calcification | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1161/STROKEAHA.114.006996 | - |
dc.identifier.scopusid | 2-s2.0-84920263297 | - |
dc.identifier.wosid | 000346735800039 | - |
dc.identifier.bibliographicCitation | Stroke, v.46, no.1, pp 151 - + | - |
dc.citation.title | Stroke | - |
dc.citation.volume | 46 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 151 | - |
dc.citation.endPage | + | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | TRANSIENT ISCHEMIC ATTACK | - |
dc.subject.keywordPlus | TRANSCRANIAL DOPPLER | - |
dc.subject.keywordPlus | COMPUTED-TOMOGRAPHY | - |
dc.subject.keywordPlus | CEREBRAL-ISCHEMIA | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | STROKE | - |
dc.subject.keywordPlus | CALCIUM | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | INFARCTION | - |
dc.subject.keywordAuthor | coronary artery disease | - |
dc.subject.keywordAuthor | intracranial atherosclerosis | - |
dc.subject.keywordAuthor | transcranial Doppler ultrasound | - |
dc.subject.keywordAuthor | vascular calcification | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.