Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops
DC Field | Value | Language |
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dc.contributor.author | Seo, Du Ri | - |
dc.contributor.author | Ha, Seung Joo | - |
dc.date.accessioned | 2021-08-11T21:44:48Z | - |
dc.date.available | 2021-08-11T21:44:48Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2314-6133 | - |
dc.identifier.issn | 2314-6141 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/11515 | - |
dc.description.abstract | Purpose. To compare the ocular pulse amplitude (OPA) lowering effects of preservative-free tafluprost and dorzolamide-timolol fixed combination (DTFC) using dynamic contour tonometry. Methods. In total, 66 eyes of 66 patients with normal tension glaucoma (NTG) (n = 34) or primary open angle glaucoma (POAG) (n = 32) were included. Patients were divided into two groups: the preservative-free tafluprost-treated group (n = 33) and the preservative-free DTFC-treated group (n = 33). Intraocular pressure (IOP) was measured using Goldmann applanation tonometry (GAT). OPA was measured using dynamic contour tonometry; corrected OPA (cOPA) was calculated at baseline and at 1 week and 1, 3, and 6 months after treatment. Results. After 6 months of treatment, tafluprost significantly reduced IOP (P < 0.001). The OPA lowering effects differed significantly between the two treatment groups (P = 0.003). The cOPA-lowering effect of tafluprost (1.09 mm Hg) was significantly greater than that of DTFC (0.36 mm Hg) after 6 months of treatment (P = 0.01). Conclusions. Tafluprost and DTFC glaucoma treatments provided marked OPA and IOP lowering effects. Tafluprost had a greater effect than DTFC; thus, this drug is recommended for patients at risk of glaucoma progression, due to the high OPA caused by large fluctuations in IOP. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Hindawi Publishing Corporation | - |
dc.title | Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1155/2015/435874 | - |
dc.identifier.scopusid | 2-s2.0-84947225833 | - |
dc.identifier.wosid | 000364064700001 | - |
dc.identifier.bibliographicCitation | BioMed Research International, v.2015 | - |
dc.citation.title | BioMed Research International | - |
dc.citation.volume | 2015 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordPlus | OPEN-ANGLE GLAUCOMA | - |
dc.subject.keywordPlus | DYNAMIC CONTOUR TONOMETRY | - |
dc.subject.keywordPlus | ELEVATED INTRAOCULAR-PRESSURE | - |
dc.subject.keywordPlus | RETINAL BLOOD-FLOW | - |
dc.subject.keywordPlus | NORMAL-TENSION | - |
dc.subject.keywordPlus | TOLERABILITY | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | IOP | - |
dc.subject.keywordAuthor | Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free | - |
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