Carpesium abrotanoides extract inhibits inducible nitric oxide synthase expression induced by toll-like receptor agonists
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Eun-Kyeong | - |
dc.contributor.author | Jeong, Do-Won | - |
dc.contributor.author | Lim, Se Jin | - |
dc.contributor.author | Gu, Gyo-Jeong | - |
dc.contributor.author | Ahn, Sang-Il | - |
dc.contributor.author | Kim, Ji-Soo | - |
dc.contributor.author | Paek, Ji Hun | - |
dc.contributor.author | Kim, Songmun | - |
dc.contributor.author | Hong, Jae Seung | - |
dc.contributor.author | Lim, Soon Sung | - |
dc.contributor.author | Youn, Hyung-Sun | - |
dc.date.accessioned | 2021-08-11T22:25:06Z | - |
dc.date.available | 2021-08-11T22:25:06Z | - |
dc.date.issued | 2014-10 | - |
dc.identifier.issn | 1226-7708 | - |
dc.identifier.issn | 2092-6456 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/11814 | - |
dc.description.abstract | Inflammation is a pathological and physiological process which is known to be involved in numerous diseases, while it is notable that a considerable proportion of chronic inflammatory diseases overlap with the development of cancer. One of the most important proteins for inflammatory responses is inducible nitric oxide synthase (iNOS). The present study investigated the effect of the extract of Carpesium abrotanoides L. (ECA) on inflammation by modulating iNOS expression induced by toll-like receptors (TLRs) agonists in murine macrophages. ECA suppressed iNOS expression induced by lipopolysaccharide (TLR4 agonist), macrophage-activating lipopeptide 2-kDa (TLR2 and TLR6 agonist), and polyriboinosinic polyribocytidylic acid (TLR3 agonist). All the results suggest that ECA can modulate TLR signaling pathways and subsequent chronic inflammatory responses. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국식품과학회 | - |
dc.title | Carpesium abrotanoides extract inhibits inducible nitric oxide synthase expression induced by toll-like receptor agonists | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.1007/s10068-014-0223-0 | - |
dc.identifier.scopusid | 2-s2.0-84918535110 | - |
dc.identifier.wosid | 000343813000037 | - |
dc.identifier.bibliographicCitation | Food Science and Biotechnology, v.23, no.5, pp 1637 - 1641 | - |
dc.citation.title | Food Science and Biotechnology | - |
dc.citation.volume | 23 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1637 | - |
dc.citation.endPage | 1641 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001925359 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | INFLAMMATORY CELLS | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | RECOGNITION | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | PATHWAY | - |
dc.subject.keywordPlus | TBK1 | - |
dc.subject.keywordAuthor | Carpesium abrotanoides | - |
dc.subject.keywordAuthor | toll-like receptor | - |
dc.subject.keywordAuthor | inflammation | - |
dc.subject.keywordAuthor | iNOS | - |
dc.subject.keywordAuthor | lipopolysaccharide | - |
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