A pilot proof-of-concept study of a modified device for one-step endoscopic ultrasound-guided biliary drainage in a new experimental biliary dilatation animal model
- Authors
- Lee, Tae Hoon; Choi, Jun Hyuck; Lee, Sang Soo; Cho, Hyun Deuk; Seo, Dong Wan; Park, Sang-Heum; Lee, Sung Koo; Kim, Myung-Hwan; Park, Do Hyun
- Issue Date
- 21-May-2014
- Publisher
- Baishideng Publishing Group
- Keywords
- Endoscopic ultrasound; Biliary drainage; Biliary dilation; Feasibility; Complications
- Citation
- World Journal of Gastroenterology, v.20, no.19, pp 5859 - 5866
- Pages
- 8
- Journal Title
- World Journal of Gastroenterology
- Volume
- 20
- Number
- 19
- Start Page
- 5859
- End Page
- 5866
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/12197
- DOI
- 10.3748/wjg.v20.i19.5859
- ISSN
- 1007-9327
2219-2840
- Abstract
- AIM: To evaluate the technical feasibility of a modified tapered metal tip and low profile introducer for one-step endoscopic ultrasound (EUS)-guided biliary drainage (EUS-BD) in a new experimental biliary dilatation porcine model. METHODS: A novel dedicated device for one-step EUS-guided biliary drainage system (DEUS) introducer has size 3F tapered catheter with size 4F metal tip for simple puncture of the intestinal wall and liver parenchyma without graded dilation. A self-expandable metal stent, consisting of both uncovered and nitinol-covered portions, was preloaded into DEUS introducer. After establishment of a biliary dilatation model using endoscopic hemoclips or band ligation with argon plasma coagulation in 9 mini-pigs, EUS-BD using a DEUS was performed following 19-G needle puncture without the use of fistula dilation devices. RESULTS: One-step EUS-BD was technically successful in seven pigs [7/9 (77.8%) as intention to treat] without the aid of devices for fistula dilation from the high body of stomach or far distal esophagus to the intrahepatic (n = 2) or common hepatic (n = 5) duct. Primary technical failure occurred in two cases that did not show adequate biliary dilatation. In seven pigs with a successful bile duct dilatation, the technical success rate was 100% (7/7 as per protocol). Median procedure time from confirmation of the dilated bile duct to successful placement of a metallic stent was 10 min (IQR; 8.9-18.1). There were no immediate procedure-related complications. CONCLUSION: Modified tapered metal tip and low profile introducer may be technically feasible for one-step EUS-BD in experimental porcine model. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.
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Collections - College of Medicine > Department of Pathology > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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