Risk factors for hospital-acquired pneumonia caused by carbapenem-resistant Gram-negative bacteria in critically ill patients: a multicenter study in Korea
- Authors
- Kim, Tark; Chong, Yong Pil; Park, Seong Yeon; Jeon, Min-Hyok; Choo, Eun Joo; Chung, Jin-Won; Lee, Hyun Kyung; Moon, Chisook; Kim, Dong-Min; Peck, Kyong Ran; Kim, Yang Soo
- Issue Date
- Apr-2014
- Publisher
- Elsevier BV
- Keywords
- Risk factor; Hospital-acquired pneumonia; Carbapenem-resistant Gram-negative; bacteria
- Citation
- Diagnostic Microbiology and Infectious Disease, v.78, no.4, pp 457 - 461
- Pages
- 5
- Journal Title
- Diagnostic Microbiology and Infectious Disease
- Volume
- 78
- Number
- 4
- Start Page
- 457
- End Page
- 461
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/12322
- DOI
- 10.1016/j.diagmicrobio.2013.08.011
- ISSN
- 0732-8893
1879-0070
- Abstract
- We performed a case-control study to identify risk factors of carbapenem-resistant Gram-negative bacteria (CRGNB) as an increasing cause of hospital-acquired pneumonia (HAP). The study included critically ill adult patients with HAP whose microbial etiology was identified at eight tertiary centers in Korea between June 2008 and December 2009. Eighty two patients with 86 isolates of CRGNB (62 Acinetobacter baumannii, 14 Pseudomonas aeruginosa, and 10 Stenotrophomonas maltophilia) were included in the case group, and 122 patients with carbapenem-susceptible Gram-negative bacteria were included in the control group. Diabetes mellitus (adjusted odds ratio [aOR] 2.82, 95% confidence interval [95% CI] 1.25-6.38), radiologic score (aOR 4.56, 95% CI 2.36-8.81), prior fluoroquinolone (aOR 2.39. 95% CI = 1.07-5.35), or carbapenem usage (aOR 2.82, 95% Cl 1.75-17.83) were found to be independent risk factors. Fluoroquinolone and carbapenem should be cautiously used to avoid HAP caused by CRGNB. (C) 2014 Elsevier Inc. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.