Special consideration is required for the component-resolved diagnosis of egg allergy in infants
DC Field | Value | Language |
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dc.contributor.author | Kim, Jihyun | - |
dc.contributor.author | Lee, Jeongok | - |
dc.contributor.author | Park, Mi-Ran | - |
dc.contributor.author | Han, Youngshin | - |
dc.contributor.author | Shin, Meeyong | - |
dc.contributor.author | Ahn, Kangmo | - |
dc.date.accessioned | 2021-08-11T23:26:58Z | - |
dc.date.available | 2021-08-11T23:26:58Z | - |
dc.date.issued | 2014-01 | - |
dc.identifier.issn | 1081-1206 | - |
dc.identifier.issn | 1534-4436 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/12576 | - |
dc.description.abstract | Background: There are few reports regarding differences in reactivity to the major egg allergens according to children's age, although component-resolved diagnosis is gradually being used. Objective: To investigate differences in reactivity to major egg allergens among various age groups of children with egg allergy. Methods: Twenty-seven patients diagnosed with egg allergy were included. Egg allergy was defined as a convincing history of reproducible symptoms within 2 hours of egg consumption and an egg white-specific IgE level of at least 0.35 kU(A)/L. Patients were divided into 3 age groups: younger than 12 months (group A, 7 subjects), 12 to 23 months (group B, 8 subjects), and at least 24 months (group C, 12 subjects). Immunoblotting and enzyme-linked immunosorbent assay investigated IgE reactivity toward ovalbumin, ovomucoid, and ovotransferrin in eggs. Results: Immunoblotting analysis showed that all patients in group A reacted to ovalbumin, whereas reactions to other proteins were not detected. All patients in group B displayed a reaction to ovalbumin and ovomucoid. IgE binding to ovotransferrin was shown in 3 patients in group B. All patients in group C displayed reactivity to ovalbumin, 5 patients showed a reaction to ovomucoid, and 8 patients displayed a reaction to ovotransferrin. As a patient's age increased, specific IgE binding to ovalbumin and ovotransferrin increased (P = .011 and .004). Conclusion: IgE reactivity to egg allergens differs according to children's ages. (C) 2014 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | American College of Allergy, Asthma, & Immunology | - |
dc.title | Special consideration is required for the component-resolved diagnosis of egg allergy in infants | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1016/j.anai.2013.09.010 | - |
dc.identifier.scopusid | 2-s2.0-84890569417 | - |
dc.identifier.wosid | 000328644000014 | - |
dc.identifier.bibliographicCitation | Annals of Allergy, Asthma and Immunology, v.112, no.1, pp 53 - 57 | - |
dc.citation.title | Annals of Allergy, Asthma and Immunology | - |
dc.citation.volume | 112 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 53 | - |
dc.citation.endPage | 57 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Allergy | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Allergy | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | WHITE-SPECIFIC IGE | - |
dc.subject.keywordPlus | FOOD ALLERGY | - |
dc.subject.keywordPlus | HENS EGG | - |
dc.subject.keywordPlus | ATOPIC-DERMATITIS | - |
dc.subject.keywordPlus | NATURAL-HISTORY | - |
dc.subject.keywordPlus | MATERNAL INTAKE | - |
dc.subject.keywordPlus | KOREAN INFANTS | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | OVALBUMIN | - |
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