공압식 박동형 심실보조장치의 공압관 내 압력 측정을 통한 박출량 추정

Abstract

A Ventricular assist device (VAD) is one of the most efficient treatments to raise the survivability of theend stage heart failure patient. However, some of LVAD patients have died for the failures and improper control ofLVAD. To detect critical dangers in LVAD, the monitoring methods of LVAD outflow have been requested, becauseit can be affected by patient’s hemodynamic states and abnormal conditions of LVAD. In the case of an external pulsatileLVAD, the air movement through the air line can be used to estimate LVAD outflow. In this study, the air movementin the air-line of the extracorporeal pulsatile LVAD was measured with a differential pressure sensor betweendifferent points. The precise estimation of air movement could be achieved by additional measurement of air pressure. In a series of in-vitro experiments, the LVAD outflow were changed according to the afterload of LVAD andthe differential pressure of LVAD didn’t have close correlation with the LVAD outflow that were measured with anultrasonic flowmeter at the same time. However, new precise estimation with the data from differential pressure andone point pressure in the air-line showed higher correlations with LVAD outflow.