Optical coherence tomographic findings of crystal deposits in the lens and cornea in Bietti crystalline corneoretinopathy associated with mutation in the CYP4V2 gene
- Authors
- Chung, Jin Kwon; Shin, Jin Hee; Jeon, Byung-Ryul; Ki, Chang-Seok; Park, Tae Kwann
- Issue Date
- Sep-2013
- Publisher
- Springer Verlag
- Keywords
- Bietti crystalline dystrophy; Cornea; Crystalline deposits; Crystalline lens
- Citation
- Japanese Journal of Ophthalmology, v.57, no.5, pp 447 - 450
- Pages
- 4
- Journal Title
- Japanese Journal of Ophthalmology
- Volume
- 57
- Number
- 5
- Start Page
- 447
- End Page
- 450
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13395
- DOI
- 10.1007/s10384-013-0256-6
- ISSN
- 0021-5155
1613-2246
- Abstract
- We report the optical coherence tomography (OCT) findings of crystalline deposits in the cornea and lens of a patient with Bietti crystalline dystrophy (BCD), thus providing evidence for a better understanding of the pathophysiology of BCD. A 49-year-old man showing typical chorioretinal degeneration with a CYP4V2 mutation was diagnosed with BCD. The anterior segment OCT images clearly showed flat hyperreflective plaques just beneath the corneal epithelium and in the lens epithelium. The crystals were not located on the outer surface of the lens capsule as previously described but on the inner surface of the anterior capsule. This finding suggests that the crystals in the lens of patients with BCD may be produced in the same way as corneal or retinal crystalline deposits and therefore result from a systemic abnormality of lipid metabolism rather than by previously considered possibilities, such as release from the retina adhering to the lens capsule.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Ophthalmology > 1. Journal Articles
- College of Medicine > Department of Clinical Pathology > 1. Journal Articles
- College of Medicine > Department of Ophthalmology > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13395)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.