Evaluation of vitamin D level in patients from neurosurgical intensive care unit star(.)
DC Field | Value | Language |
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dc.contributor.author | Yi, Ho Jun | - |
dc.contributor.author | Jeong, Je Hoon | - |
dc.contributor.author | Jin, Eun-Sun | - |
dc.contributor.author | Shin, Il Young | - |
dc.contributor.author | Hwang, Hyung Sik | - |
dc.contributor.author | Moon, Seung-Myung | - |
dc.date.accessioned | 2021-08-12T01:14:25Z | - |
dc.date.available | 2021-08-12T01:14:25Z | - |
dc.date.issued | 2013-06 | - |
dc.identifier.issn | 1673-5374 | - |
dc.identifier.issn | 1876-7958 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13649 | - |
dc.description.abstract | Vitamin D plays an important role in maintaining normal bone metabolism. Recent studies have suggested that vitamin D influences many other physiological processes, including muscle function, cardiovascular homeostasis, nerve function, and immune response. Furthermore, accumulated evidence suggests that vitamin D also mediates the immune system response to infection. Critical neurosurgical patients have higher infection and mortality rates. To correlate vitamin D deficiency to the immunological status of neurosurgical intensive care unit patients, we detected serum vitamin D level in 15 patients with clinically suspected infection and 10 patients with confirmed infection. Serum level of 25-hydroxyvitamin D, the primary circulating form of vitamin D, was significantly decreased in patients with suspected or confirmed infection after a 2-week neurosurgical intensive care unit hospitalization, while serum level of 1,25-dihydroxyvitamin D, the active form of vitamin D, was significantly decreased in patients after a 4-week neurosurgical intensive care unit hospitalization. These findings suggest that vitamin D deficiency is linked to the immunological status of neurosurgical intensive care unit patients and vitamin D supplementation can improve patient's immunological status. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Neural Regeneration Research | - |
dc.title | Evaluation of vitamin D level in patients from neurosurgical intensive care unit star(.) | - |
dc.type | Article | - |
dc.publisher.location | 인도 | - |
dc.identifier.doi | 10.3969/j.issn.1673-5374.2013.16.010 | - |
dc.identifier.wosid | 000321121400010 | - |
dc.identifier.bibliographicCitation | Neural Regeneration Research, v.8, no.16, pp 1528 - 1534 | - |
dc.citation.title | Neural Regeneration Research | - |
dc.citation.volume | 8 | - |
dc.citation.number | 16 | - |
dc.citation.startPage | 1528 | - |
dc.citation.endPage | 1534 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | D DEFICIENCY | - |
dc.subject.keywordPlus | HYPOVITAMINOSIS D | - |
dc.subject.keywordPlus | D INSUFFICIENCY | - |
dc.subject.keywordPlus | IMMUNE-SYSTEM | - |
dc.subject.keywordPlus | 25-HYDROXYCHOLECALCIFEROL | - |
dc.subject.keywordPlus | CYTOCHROME-P-450 | - |
dc.subject.keywordPlus | CHOLECALCIFEROL | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordAuthor | neural regeneration | - |
dc.subject.keywordAuthor | vitamin D | - |
dc.subject.keywordAuthor | white blood cell | - |
dc.subject.keywordAuthor | immune deficiency | - |
dc.subject.keywordAuthor | infectious diseases | - |
dc.subject.keywordAuthor | intensive care unit | - |
dc.subject.keywordAuthor | neurosurgery | - |
dc.subject.keywordAuthor | neuroregeneration | - |
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