Follow-up of primary Sjogren's syndrome patients presenting positive anti-cyclic citrullinated peptides antibody
DC Field | Value | Language |
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dc.contributor.author | Ryu, Yang-Seon | - |
dc.contributor.author | Park, Sung-Hwan | - |
dc.contributor.author | Lee, Jennifer | - |
dc.contributor.author | Kwok, Seung-Ki | - |
dc.contributor.author | Ju, Ji-Hyeon | - |
dc.contributor.author | Kim, Ho-Youn | - |
dc.contributor.author | Jeon, Chan-Hong | - |
dc.date.accessioned | 2021-08-12T01:14:27Z | - |
dc.date.available | 2021-08-12T01:14:27Z | - |
dc.date.issued | 2013-06 | - |
dc.identifier.issn | 0172-8172 | - |
dc.identifier.issn | 1437-160X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13652 | - |
dc.description.abstract | Anti-cyclic citrullinated peptide antibody (anti-CCP antibody) is very useful for the diagnosis of rheumatoid arthritis (RA) and is associated with articular erosions. The specificity of anti-CCP antibody in the diagnosis of RA has been reported to be about 95 %. Because of its higher specificity in RA, we assessed the clinical features of primary Sjogren's syndrome (pSS) who were positive for anti-CCP antibody. We assessed the clinical features of 405 pSS patients. After 60 (range 7-98) months, 23 (5.6 %) patients previously diagnosed with pSS had progressed to RA. Comparing the anti-CCP positive group with the negative group, laboratory test results for anti-CCP titer and rheumatoid factor positivity with respect to clinical outcome and progression to RA, arthralgia and arthritis were significantly different. Multivariate regression analysis also showed that anti-CCP antibody titer was independently associated with progression to RA. The odds ratio of anti-CCP positivity in terms of progression to RA was 2.5 (95 % CI 1.7-3.7). Testing for anti-CCP antibody in pSS patients with arthritis may allow for the prediction of progression to RA. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Follow-up of primary Sjogren's syndrome patients presenting positive anti-cyclic citrullinated peptides antibody | - |
dc.type | Article | - |
dc.publisher.location | 독일 | - |
dc.identifier.doi | 10.1007/s00296-012-2572-4 | - |
dc.identifier.scopusid | 2-s2.0-84878744987 | - |
dc.identifier.wosid | 000319517000011 | - |
dc.identifier.bibliographicCitation | Rheumatology International, v.33, no.6, pp 1443 - 1446 | - |
dc.citation.title | Rheumatology International | - |
dc.citation.volume | 33 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1443 | - |
dc.citation.endPage | 1446 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | RHEUMATOID-ARTHRITIS | - |
dc.subject.keywordPlus | ARTICULAR MANIFESTATIONS | - |
dc.subject.keywordAuthor | Anti-CCP antibody | - |
dc.subject.keywordAuthor | Primary Sjogren's syndrome | - |
dc.subject.keywordAuthor | Rheumatoid arthritis | - |
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