The use of fibrin matrix-mixed gel-type autologous chondrocyte implantation in the treatment for osteochondral lesions of the talus
- Authors
- Lee, Kyung Tai; Kim, Jin Su; Young, Ki Won; Lee, Young Koo; Park, Young Uk; Kim, Yong Hoon; Cho, Hun Ki
- Issue Date
- Jun-2013
- Publisher
- Springer Verlag
- Keywords
- Talus; Osteochondral lesion; Autologous chondrocyte implantation; Arthroscopy; Donor
- Citation
- Knee Surgery, Sports Traumatology, Arthroscopy, v.21, no.6, pp 1251 - 1260
- Pages
- 10
- Journal Title
- Knee Surgery, Sports Traumatology, Arthroscopy
- Volume
- 21
- Number
- 6
- Start Page
- 1251
- End Page
- 1260
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13658
- DOI
- 10.1007/s00167-012-2096-1
- ISSN
- 0942-2056
1433-7347
- Abstract
- This study assessed the clinical results and second-look arthroscopy after fibrin matrix-mixed gel-type autologous chondrocyte implantation to treat osteochondral lesions of the talus. Chondrocytes were harvested from the cuboid surface of the calcaneus in 38 patients and cultured, and gel-type autologous chondrocyte implantation was performed with or without medial malleolar osteotomy. Preoperative American orthopedic foot and ankle society ankle-hind foot scores, visual analogue score, Hannover scoring system and subjective satisfaction were investigated, and the comparison of arthroscopic results (36/38, 94.7 %) and MRI investigation of chondral recovery was performed. Direct tenderness and relationship to the active daily life of the donor site was evaluated. The preoperative mean ankle-hind foot scores (71 +/- A 14) and Hannover scoring system (65 +/- A 10) had increased to 91 +/- A 12 and 93 +/- A 14, respectively, at 24-month follow-up (p < 0.0001), and the preoperative visual analogue score of 58 mm had decreased to 21 mm (p < 0.0001). Regarding subjective satisfaction, 34 cases (89.5 %) reported excellent, good or fair. Chondral regeneration was analysed by second-look arthroscopy and MRI. Complications included one non-union and two delayed-unions of the osteotomy sites, and 9 ankles (9/31, 29.0 %) sustained damaged medial malleolar cartilage due to osteotomy. Marked symptoms at the biopsy site did not adversely affect the patient's active daily life. Fibrin matrix-mixed gel-type autologous chondrocyte implantation using the cuboid surface of the calcaneus as a donor can be used for treating osteochondral lesions of the talus. Therapeutic study, prospective case series, Level IV.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Orthopedic Surgery > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13658)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.