Aspirin-intolerant asthma in the Korean population: Prevalence and characteristics based on a questionnaire survey
DC Field | Value | Language |
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dc.contributor.author | Moon, Ji-Yong | - |
dc.contributor.author | Kim, Sang-Heon | - |
dc.contributor.author | Kim, Tae-Bum | - |
dc.contributor.author | Kim, Sae-Hoon | - |
dc.contributor.author | Chang, Yoon-Seok | - |
dc.contributor.author | Lee, Jae Hyun | - |
dc.contributor.author | Cho, You Sook | - |
dc.contributor.author | Park, Jung Won | - |
dc.contributor.author | Jang, An-Soo | - |
dc.contributor.author | Park, Choon-Sik | - |
dc.contributor.author | Nahm, Dong-Ho | - |
dc.contributor.author | Cho, Young-Joo | - |
dc.contributor.author | Cho, Sang-Heon | - |
dc.contributor.author | Choi, Byoung-Whui | - |
dc.contributor.author | Moon, Hee-Bom | - |
dc.contributor.author | Yoon, Ho Joo | - |
dc.date.accessioned | 2021-08-12T01:25:31Z | - |
dc.date.available | 2021-08-12T01:25:31Z | - |
dc.date.issued | 2013-02 | - |
dc.identifier.issn | 0954-6111 | - |
dc.identifier.issn | 1532-3064 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13962 | - |
dc.description.abstract | Background: Aspirin-intolerant asthma is a unique clinical syndrome characterized by acute bronchoconstriction following the administration of aspirin and/or non-steroidal anti-inflammatory drugs. Objective: We assessed the prevalence and investigated the demographic and clinical characteristics of adult patients with aspirin-intolerant asthma in Korea. Methods: Using an adult asthma cohort (COREA) from 11 university hospitals in Korea, we analyzed the prevalence of aspirin-intolerant asthma, defined as a positive response to the question: "Have you ever experienced dyspnea and cough after taking an aspirin or any NSAID (cold medicine)?" Demographic and clinical characteristics were compared between patients with aspirin-intolerant asthma and aspirin-tolerant asthma. Results: Aspirin-intolerant asthma was reported in 68 (5.8%) of 1173 adult asthmatics (age 15 84). Patients with aspirin-intolerant asthma had a lower mean age (43.9 +/- 13.4 vs. 49.0 +/- 15.6, P = 0.003) and a higher prevalence of rhinosinusitis (77.9% vs. 61.7%, P = 0.012) and atopic dermatitis (16.2% vs. 5.7%, P = 0.001) than aspirin-tolerant asthma patients. There were no significant differences in lung function, asthma severity or the use of asthma controllers. However, aspirin-intolerant asthma was associated with greater use of healthcare services over a lifetime and over the past 12 months. Aspirin-intolerant asthma was significantly associated with emergency room visits over the past 12 months (P = 0.029, OR 2.19, 95% Cl 1.08-4.42). Conclusion: Based on histories, the prevalence of aspirin-intolerant asthma is 5.8% among adult asthma patients in Korea. Aspirin-intolerant asthma is associated with lower age, higher prevalence of rhinosinusitis and atopic dermatitis, and more frequent exacerbations. (C) 2012 Published by Elsevier Ltd. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | W. B. Saunders Co., Ltd. | - |
dc.title | Aspirin-intolerant asthma in the Korean population: Prevalence and characteristics based on a questionnaire survey | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1016/j.rmed.2012.10.020 | - |
dc.identifier.scopusid | 2-s2.0-84872120319 | - |
dc.identifier.wosid | 000314556000005 | - |
dc.identifier.bibliographicCitation | Respiratory Medicine, v.107, no.2, pp 202 - 208 | - |
dc.citation.title | Respiratory Medicine | - |
dc.citation.volume | 107 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 202 | - |
dc.citation.endPage | 208 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | EXACERBATED RESPIRATORY-DISEASE | - |
dc.subject.keywordPlus | NATURAL-HISTORY | - |
dc.subject.keywordPlus | CLINICAL CHARACTERISTICS | - |
dc.subject.keywordPlus | ADULT ASTHMA | - |
dc.subject.keywordPlus | HYPERSENSITIVITY | - |
dc.subject.keywordPlus | PATHOGENESIS | - |
dc.subject.keywordPlus | SENSITIVITY | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | SEVERITY | - |
dc.subject.keywordAuthor | Aspirin-intolerant asthma | - |
dc.subject.keywordAuthor | Prevalence | - |
dc.subject.keywordAuthor | Characteristics | - |
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