The Relationship between Uterine Myoma Growth and the Endocrine Disruptor in Postmenopausal Women
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정은호 | - |
dc.contributor.author | 홍기연 | - |
dc.contributor.author | 김병윤 | - |
dc.contributor.author | 박성남 | - |
dc.contributor.author | 이해혁 | - |
dc.contributor.author | 나용진 | - |
dc.contributor.author | 정남궁 | - |
dc.date.accessioned | 2021-08-12T01:27:35Z | - |
dc.date.available | 2021-08-12T01:27:35Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2288-6478 | - |
dc.identifier.issn | 2288-6761 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/14127 | - |
dc.description.abstract | Objectives: To investigate the number of leiomyoma patients-exposed to bisphenol A (BPA) and to observe whether the serum concentration of BPA is related to leiomyoma growth. Methods: A total of 158 patients were recruited for this study. Leiomyoma patients were divided into three groups, mild (n = 48), moderate (n = 32) and severe (n = 28), according to the size of leiomyomas. The control (n = 30) group was defined as having no leiomyomas. Transvaginal ultrasonography was used to identify and measure the leiomyomas. Serum BPA concentrations were measured by enzyme-linked immunosorbent assay. Results: BPA was detected in 87.0% out of a total of 158 samples, and in 86.0% out of 108 leiomyoma patients. In detail, the detection rates of serum BPA were 88.0% in the control group, 77.2% in the mild group, 90.0% in the moderate group and 96.0% in the severe group. The mean BPA concentration in the control group was 0.558 ± 0.097 ng/mL, the leiomyoma groups, the mean BPA concentrations were 0.274 ± 0.063 ng/mL (mild), 0.346 ± 0.064 ng/mL (moderate) and 0.647 ± 0.039 ng/mL (severe) (P = 0.0003). Values repres ent the mean ± standard error. Conclusion: The detection rates of serum BPA in the control and leiomyoma groups were 88.0% and 86.0%, respectively. However, there was no significant difference in the serum BPA concentrations between the control and leiomyoma groups. To verify the effect of BPA on leiomyoma growth, a close and sequential monitoring is recommended for people who are at risk for uterine leiomyoma. (J Menopausal Med 2013;19:130-134) | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한폐경학회 | - |
dc.title | The Relationship between Uterine Myoma Growth and the Endocrine Disruptor in Postmenopausal Women | - |
dc.title.alternative | The Relationship between Uterine Myoma Growth and the Endocrine Disruptor in Postmenopausal Women | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.bibliographicCitation | 대한폐경학회지, v.19, no.3, pp 130 - 134 | - |
dc.citation.title | 대한폐경학회지 | - |
dc.citation.volume | 19 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 130 | - |
dc.citation.endPage | 134 | - |
dc.identifier.kciid | ART001828188 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kciCandi | - |
dc.subject.keywordAuthor | Endocrine disruptors | - |
dc.subject.keywordAuthor | Leiomyoma | - |
dc.subject.keywordAuthor | Uterus | - |
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