Pulmonary hypertension associated with rheumatic diseases: baseline characteristics from the Korean registry
DC Field | Value | Language |
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dc.contributor.author | Jeon, Chan Hong | - |
dc.contributor.author | Chai, Ji-Young | - |
dc.contributor.author | Seo, Young-Il | - |
dc.contributor.author | Jun, Jae-Bum | - |
dc.contributor.author | Koh, Eun-Mi | - |
dc.contributor.author | Lee, Soo-Kon | - |
dc.date.accessioned | 2021-08-12T02:44:37Z | - |
dc.date.available | 2021-08-12T02:44:37Z | - |
dc.date.issued | 2012-10 | - |
dc.identifier.issn | 1756-1841 | - |
dc.identifier.issn | 1756-185X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/14791 | - |
dc.description.abstract | Objectives The REgistry of Pulmonary Hypertension Associated with Rheumatic Disease (REOPARD) was established in Korea. The baseline data are described from the second year of the registry's operation. Methods Patients with a connective tissue disease (CTD) who met the modified definition of the WHO group I pulmonary arterial hypertension (PAH) were enrolled. PAH was defined as a systolic pulmonary arterial pressure >similar to 40 similar to mmHg by echocardiography or mean pulmonary arterial pressure >similar to 25 similar to mmHg by right heart catheterization. Hemodynamic parameters and clinical data such as demographics, functional class, underlying disease, organ involvement, laboratory tests and current treatment were recorded. Results A total of 321 patients were enrolled during the 2-year study period from 2008 to 2010. The mean age of the patients at registration was 51.9 similar to years and 87.5% were female. Most patients were diagnosed by echocardiography and only 24 patients (7.5%) underwent cardiac catheterization. Exertional dyspnea was present in 63.6% of patients and 31.8% were New York Heart Association class III or IV. Among the patients, systemic lupus erythematosus accounted for 35.3%, systemic sclerosis 28.3%, rheumatoid arthritis 7.8%, overlap syndrome 9.0%, and mixed connective tissue disease 5.9%. There were no significant differences in hemodynamics, functional class, diffusing capacity and N-terminal pro-brain natriuretic peptide levels between the disease subgroups. Treatments consisted of calcium antagonists (57.0%), endothelin antagonists (32.7%), prostanoids (27.1%), phosphodiesterase-5 inhibitors (14.3%) and combinations (37.4%). Conclusion Compared with previous studies, the results showed some differences: underlying diseases, functional status and treatments. This may be due to differences in ethnic background and diagnostic methods of our study. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | Pulmonary hypertension associated with rheumatic diseases: baseline characteristics from the Korean registry | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1111/j.1756-185X.2012.01815.x | - |
dc.identifier.scopusid | 2-s2.0-84867905967 | - |
dc.identifier.wosid | 000310077300001 | - |
dc.identifier.bibliographicCitation | International Journal of Rheumatic Diseases, v.15, no.5, pp E80 - E89 | - |
dc.citation.title | International Journal of Rheumatic Diseases | - |
dc.citation.volume | 15 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | E80 | - |
dc.citation.endPage | E89 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject.keywordPlus | BRAIN NATRIURETIC PEPTIDE | - |
dc.subject.keywordPlus | ARTERIAL-HYPERTENSION | - |
dc.subject.keywordPlus | SCLEROSIS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | SCLERODERMA | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | REVEAL | - |
dc.subject.keywordAuthor | connective tissue disease | - |
dc.subject.keywordAuthor | pulmonary arterial hypertension | - |
dc.subject.keywordAuthor | registries | - |
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