Hyperplastic Polyposis Syndrome Identified with a BRAF Mutation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ahn, Hyung Su | - |
dc.contributor.author | Hong, Su Jin | - |
dc.contributor.author | Kim, Hee Kyung | - |
dc.contributor.author | Yoo, Hee Yong | - |
dc.contributor.author | Kim, Hwa Jong | - |
dc.contributor.author | Ko, Bong Min | - |
dc.contributor.author | Lee, Moon Sung | - |
dc.date.accessioned | 2021-08-12T03:27:14Z | - |
dc.date.available | 2021-08-12T03:27:14Z | - |
dc.date.issued | 2012-04 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.issn | 2005-1212 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/15277 | - |
dc.description.abstract | Hyperplastic polyposis syndrome (HPS) is a rare condition characterized by the presence of numerous hyperplastic polyps (HPs) in the colon and rectum. Patients with HPS have an increased risk of colorectal cancer. This link is associated with gene mutations, especially B type Raf kinase (BRAF). However, a case of HPS associated with gene mutations has seldom been reported in Korea. Here, we describe a case of HPS in which a BRAF mutation was present in a 34-year-old woman. She had more than 110 HPs in the stomach and colorectum, which we removed. All of the polyps were diagnosed histologically as HPs, and no adenomatous or malignant changes were noted. We performed a BRAF and K-ras mutation analysis as well as a microsatellite analysis on the resected colon polyps. BRAF mutations were found in the resected colon polyps, but there was no evidence of K-RAS mutation or microsatellite instability. (Gut Liver 2012;6:280-283) | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 거트앤리버 발행위원회 | - |
dc.title | Hyperplastic Polyposis Syndrome Identified with a BRAF Mutation | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.5009/gnl.2012.6.2.280 | - |
dc.identifier.scopusid | 2-s2.0-84860334041 | - |
dc.identifier.wosid | 000303137000018 | - |
dc.identifier.bibliographicCitation | Gut and Liver, v.6, no.2, pp 280 - 283 | - |
dc.citation.title | Gut and Liver | - |
dc.citation.volume | 6 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 280 | - |
dc.citation.endPage | 283 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001652823 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kciCandi | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | COLORECTAL-CANCER | - |
dc.subject.keywordPlus | SERRATED ADENOMAS | - |
dc.subject.keywordPlus | KRAS MUTATIONS | - |
dc.subject.keywordPlus | MICROSATELLITE INSTABILITY | - |
dc.subject.keywordPlus | COLON | - |
dc.subject.keywordPlus | PATHWAYS | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordPlus | METHYLATION | - |
dc.subject.keywordPlus | GENETICS | - |
dc.subject.keywordAuthor | Hyperplastic polyposis syndrome | - |
dc.subject.keywordAuthor | BRAF | - |
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