Gastrointestinal Metabolic Surgery for the Treatment of Diabetic Patients: A Multi-Institutional International Study
DC Field | Value | Language |
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dc.contributor.author | Lee, Wei-Jei | - |
dc.contributor.author | Hur, Kyung Yul | - |
dc.contributor.author | Lakadawala, Muffazal | - |
dc.contributor.author | Kasama, Kazunori | - |
dc.contributor.author | Wong, Simon K. H. | - |
dc.contributor.author | Lee, Yi-Chih | - |
dc.date.accessioned | 2021-08-12T03:46:14Z | - |
dc.date.available | 2021-08-12T03:46:14Z | - |
dc.date.issued | 2012-01 | - |
dc.identifier.issn | 1091-255X | - |
dc.identifier.issn | 1873-4626 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/15473 | - |
dc.description.abstract | Gastrointestinal metabolic surgery has been proposed for the treatment of not well-controlled type 2 diabetes mellitus (T2DM) patients with a body mass index (BMI) < 35 kg/m(2). This study aims to describe recent experience with surgical treatment of T2DM in Asian centers. Patients aged 20 to 70 years with not well-controlled T2DM [glycated hemoglobin (HbA1C) > 7.0%] and BMI < 35 kg/m(2) were included at five institutes between 2007 and 2010. The end point is T2DM remission, defined by fasting plasma glucose < 110 mg/dl and HbA1C < 6.0%. Of the 200 patients, 172 (86%) underwent gastric bypass, 24 (12%) underwent sleeve gastrectomy, and the other 4 underwent adjustable banding. Laparoscopic access was used in all the patients. Gender (66.5% female), age (mean 45.0 +/- 10.8), and HbA1C (mean 9.3 +/- 1.9%) did not differ between the procedure among the groups. Until now, 87 patients had 1-year data. One year after surgery, the mean BMI decreased from 28.5 +/- 3.0 to 23.4 +/- 2.3 kg/m(2) and HbA1C decreased to 6.3 +/- 0.5%. Remission of T2DM was achieved in 72.4% of the patients. Patients with a diabetes duration of < 5 years had a better diabetes remission rate than patients with duration of diabetes > 5 years (90.3% vs. 57.1%; p = 0.006). Patients with BMI > 30 kg/m(2) had a better diabetes remission rate than those with BMI < 30 kg/m(2) (78.7% vs. 62.5%; p = 0.027). Individuals who underwent gastric bypass loss more weight and had a higher diabetes remission rate than individuals who underwent restrictive-type procedures. Multivariate analysis confirmed that the duration of diabetes and the type of surgery predict the diabetes remission. No mortalities were reported and two (1.0%) patients had major morbidities. Gastrointestinal metabolic surgery is an effective treatment for not well-controlled T2DM treatment. Diabetes remission is significantly higher in those with duration of diabetes less than 5 years and BMI > 30 kg/m(2). | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Gastrointestinal Metabolic Surgery for the Treatment of Diabetic Patients: A Multi-Institutional International Study | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s11605-011-1740-2 | - |
dc.identifier.scopusid | 2-s2.0-84855346711 | - |
dc.identifier.wosid | 000298884500010 | - |
dc.identifier.bibliographicCitation | Journal of Gastrointestinal Surgery, v.16, no.1, pp 45 - 51 | - |
dc.citation.title | Journal of Gastrointestinal Surgery | - |
dc.citation.volume | 16 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 45 | - |
dc.citation.endPage | 51 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | ROUX-EN-Y | - |
dc.subject.keywordPlus | LAPAROSCOPIC SLEEVE GASTRECTOMY | - |
dc.subject.keywordPlus | MINI-GASTRIC BYPASS | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | BARIATRIC SURGERY | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | MELLITUS | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | REMISSION | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordAuthor | Gastrointestinal metabolic surgery | - |
dc.subject.keywordAuthor | Type 2 diabetes mellitus | - |
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