폐금속광산 지역주민의 요중 카드뮴 수준 및 골밀도와의 관련성Relationship between Urine Cadmium and Bone Mineral Density of Residents Around Abandoned Metal Mines
- Other Titles
- Relationship between Urine Cadmium and Bone Mineral Density of Residents Around Abandoned Metal Mines
- Authors
- 정경식; 이병국; 안승철; 김남수
- Issue Date
- 2012
- Publisher
- 한국환경보건학회
- Keywords
- Bone Mineral Density (BMD); urinary Cd; abandoned mines; osteoporosis; osteopenia
- Citation
- 한국환경보건학회지, v.38, no.4, pp 323 - 331
- Pages
- 9
- Journal Title
- 한국환경보건학회지
- Volume
- 38
- Number
- 4
- Start Page
- 323
- End Page
- 331
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/15662
- DOI
- 10.5668/JEHS.2012.38.4.323
- ISSN
- 1738-4087
2233-8616
- Abstract
- Objectives: The objective of this study was to investigate the possible effects of environmental cadmium (Cd)exposure on of bone mineral density (BMD) levels.
Methods: A total of 171 residents around abandoned mines in Chungcheongnam-do were surveyed in 2008-2011. Urinary Cd and BMD were analyzed by atomic absorption spectrometry and Dual-Energy X-ray absorptionmetry , respectively. Osteoporosis and osteopenia were defined by T-scores set by the WHO; Tscore ≥ −1.0, normal; −1.0 > T-score > −2.5, osteopenia; and T-score ≤ −2.5, osteoporosis. Logistic and multiple linear regressions were applied to estimate the association between U-Cd levels and BMD.
Results: The U-Cd geometric mean of 171 Koreans was 2.79 μg/g·cr. The U-Cd concentration was significantly higher among women (2.98 μg/g·cr) than men (2.39 μg/g·cr). With the multiple regression model, the BMD was influenced by U-Cd, BMI, and monthly income. With the logistic regression model, osteoporosis was associated with U-Cd levels (OR = 3.239, 95% CI = 1.770-5.927).
Conclusions: We conclude that exposure to cadmium is associated with an increased risk of osteoporosis
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Collections - College of Medicine > Institute of Environmental and Industrial Medicine > 1. Journal Articles
- College of Medicine > Department of Preventive Medicine > 1. Journal Articles
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