상황버섯 균사체 추출물의 면역증진 효능Immunostimulating Effect of Mycelium Extract of Phellinus linteus
- Other Titles
- Immunostimulating Effect of Mycelium Extract of Phellinus linteus
- Authors
- 이병의; 유시용; 김의한; 김영희; 곽경아; 송호연
- Issue Date
- 2012
- Publisher
- 한국생약학회
- Keywords
- Phellinus linteus mycelium; Immunostimulation; Cytokine; Peritoneal macrophage cell; Rat spleen cell.
- Citation
- 생약학회지, v.43, no.2, pp.157 - 162
- Journal Title
- 생약학회지
- Volume
- 43
- Number
- 2
- Start Page
- 157
- End Page
- 162
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/15769
- ISSN
- 0253-3073
- Abstract
- In order to investigate the immunostimulating effect of mycelia extract of Phellinus linteus (PLM) on human monocyte THP-1 and rat peritoneal macrophage cell, we examined measuring cytokine secretion (IL-6 and TNF-α). The production of IL-6 and TNF-a in human monocyte THP-1 was slight increased dose-dependently when the cells were challenged with PLM for 72 hrs. It was also observed that the treatment of PLM with LPS augmented the production of IL-6 and TNF-a in human monocyte THP-1. It was also observed that the treatment of PLM with LPS augmented the production of IL-6 and TNF-α in human monocyte THP-1. The production of IL-6 and TNF-α in rat peritoneal macrophage was significantly enhanced when the cells were treated PLM with LPS for 72 hrs. Moreover, the proliferation rate of rat spleen cells was increased in a dose dependent manner as the cells were treated with PLM and Concanavalin A.
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Collections - College of Medicine > Department of Microbiology > 1. Journal Articles
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