부착성 사상세균 Leucothrix mucor 배양액에서 분리된 GiffinisteroneB 와 Oleamide의 해조류 Ulva pertusa 부착방지 효과

Abstract

The filamentous bacterium Leucothrix mucor, an epiphyte of seaweed, showed antifouling activity against Ulva pertusa spore settlement and germling development. The chemical constituents representing the antifouling activity were identified as giffinisterone B and oleamide based on nuclear magnetic resonance (NMR) spectroscopy and mass spectroscopy (MS). Approximately 3.6 mg of giffinisterone B and 2.8 mg of oleamide were isolated from 1.6 g of Leucothrix mucor crude extract. Giffinisterone B fully inhibited spore settlement and germling development at 100 μg/mL. Oleamide inhibited spore settlement at 10 μg/mL and germling development at 100 μg/mL.