Oligonol 섭취가 온열자극 후 백혈구와 혈중 HSP70 발현 및 체온에 미치는 영향

Abstract

This study aimed to examine the effect of Oligonol intake on leukocytes, serum heat shock protein 70(HSP70), and body temperature after heat stress. Subjects were male college tennis athletes. All subjects participated in two repeated experiments with one week interval. During the 30 min intermittent half-body immersion, subjects were given 500 water with or without Oligonol(100 mg). Blood samples were taken from antecubital vein and differential leukocytes were counted. Serum HSP70 protein was analyzed by commercial ELISA kit. Skin and tympanic temperatures were measured and mean body temperatures were calculated. After half-body immersion, leukocytes increased significantly(p < 0.05). But there were no significant changes of neutrophils and monocytes in both trials(with or without Oligonol). In the case of Oligonol, lymphocytes kept increased during recovery period(p < 0.01, p < 0.05,respectively). Serum protein level of HSP70 did not changed after immersion, but it decreased 60 min after immersion with Oligonol(p < 0.05). Tympanic temperatures in Oligonol trial was maintained at lower degree overall recovery period compared with placebo trial(p < 0.05, p < 0.05, respectively). In conclusion, Oligonol intake had a benefit of reducing body temperature and accumulation of serum HSP70 protein, and of improving lymphocytes immune function after heat stress in tennis athletes.