The Impact of Hyperuricemia on In-Hospital Mortality and Incidence of Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention
DC Field | Value | Language |
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dc.contributor.author | Park, Sang-Ho | - |
dc.contributor.author | Shin, Won-Yong | - |
dc.contributor.author | Lee, Eun-Young | - |
dc.contributor.author | Gil, Hyo-Wook | - |
dc.contributor.author | Lee, Se-Whan | - |
dc.contributor.author | Lee, Seung-Jin | - |
dc.contributor.author | Jin, Dong-Kyu | - |
dc.contributor.author | Hong, Sae-Yong | - |
dc.date.accessioned | 2021-08-12T05:46:50Z | - |
dc.date.available | 2021-08-12T05:46:50Z | - |
dc.date.issued | 2011-03 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.issn | 1347-4820 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/16701 | - |
dc.description.abstract | Background: There is very little information about the relationship between hyperuricemia, acute kidney injury (AKI) and in-hospital mortality. Methods and Results: With a retrospective analysis of the medical records, 1,247 patients who had percutaneous coronary intervention (PCI) were investigated. AKI was defined as an increase in serum creatinine of >= 0.5 mg/dl or >= 50% over baseline within 7 days of PCI. The association of AKI with clinical, biochemical and procedural variables were examined. In addition, the association of hyperuricemia with in-hospital mortality was also examined. Of the 1,247 patients in the study population, 51 (4.1%) experienced AKI after PCI, 15 of whom required hemodialysis. In-hospital mortality occurred in 1.6% (20 of 1,247) in 19.6% (10 of 51) of AKI individuals, and 0.8% (10 of 1,186) of the non-AKI participants (odd ratios, 28.927; 95% confidence intervals, 11.411-73.328; P < 0.001). In our study, the most powerful predictors of these variables were acute myocardial infarction, baseline estimated glomerular filtration rate (eGFR) < 60 ml.min(-1).1.73m(-2), diabetics mellitus, anemia and hyperuricemia. Notably, the incidence of AKI after PCI markedly increased in diabetic or hyperuricemic patients with a baseline eGFR of < 60 ml.min(-1).1.73m(-2). Conclusions: It is clear that AKI develops due to multiple risk factors. Our results indicate that hyperuricemia is independently associated with an increased risk of in-hospital mortality and AKI in patients treated with PCI. (Circ J 2011; 75: 692 697) | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Japanese Circulation Society/Nihon Junkanki Gakkai | - |
dc.title | The Impact of Hyperuricemia on In-Hospital Mortality and Incidence of Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention | - |
dc.type | Article | - |
dc.publisher.location | 일본 | - |
dc.identifier.doi | 10.1253/circj.CJ-10-0631 | - |
dc.identifier.scopusid | 2-s2.0-79952330121 | - |
dc.identifier.wosid | 000287991500030 | - |
dc.identifier.bibliographicCitation | Circulation Journal, v.75, no.3, pp 692 - 697 | - |
dc.citation.title | Circulation Journal | - |
dc.citation.volume | 75 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 692 | - |
dc.citation.endPage | 697 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | CONTRAST-INDUCED NEPHROPATHY | - |
dc.subject.keywordPlus | ACUTE-RENAL-FAILURE | - |
dc.subject.keywordPlus | SERUM URIC-ACID | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | ENDOTHELIAL FUNCTION | - |
dc.subject.keywordPlus | DIABETES-MELLITUS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | INSUFFICIENCY | - |
dc.subject.keywordPlus | NEPHROTOXICITY | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordAuthor | Ischemic heart disease | - |
dc.subject.keywordAuthor | Kidney | - |
dc.subject.keywordAuthor | Percutaneous coronary intervention | - |
dc.subject.keywordAuthor | Renal failure | - |
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