The Effect of Low-dose Ketamine on Post-caesarean Delivery Analgesia after Spinal Anesthesia
DC Field | Value | Language |
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dc.contributor.author | Han, Seung Yeup | - |
dc.contributor.author | Jin, Hee Cheol | - |
dc.contributor.author | Yang, Woo Dae | - |
dc.contributor.author | Lee, Joon Ho | - |
dc.contributor.author | Cho, Seong Hwan | - |
dc.contributor.author | Chae, Won Seok | - |
dc.contributor.author | Lee, Jeong Seok | - |
dc.contributor.author | Kim, Yong Ik | - |
dc.date.accessioned | 2021-09-10T05:24:53Z | - |
dc.date.available | 2021-09-10T05:24:53Z | - |
dc.date.issued | 2013-07 | - |
dc.identifier.issn | 2005-9159 | - |
dc.identifier.issn | 2093-0569 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/18665 | - |
dc.description.abstract | Background: Ketamine, an N-methyl-D-aspartate receptor antagonist, might play a role in postoperative analgesia, but its effect on postoperative pain after caesarean section varies with study design. We investigated whether the preemptive administration of low-dose intravenous ketamine decreases postoperative opioid requirement and postoperative pain in parturients receiving intravenous fentanyl with patient- controlled analgesia (PCA) following caesarean section. Methods: Spinal anesthesia was performed in 40 parturients scheduled for elective caesarean section. Patients in the ketamine group received a 0.5 mg/kg ketamine bolus intravenously followed by 0.25 mg/kg/h continuous infusion during the operation. The control group received the same volume of normal saline. Immediately after surgery, the patients were connected to a PCA device set to deliver 25-mu g fentanyl as an intravenous bolus with a 15-min lockout interval and no continuous dose. Postoperative pain was assessed using the cumulative dose of fentanyl and visual analog scale (VAS) scores at 2, 6, 24, and 48 h postoperatively. Results: Significantly less fentanyl was used in the ketamine group 2 h after surgery (P = 0.033), but the difference was not significant at 6, 12, and 24 h postoperatively. No significant differences were observed between the VAS scores of the two groups at 2, 6, 12, and 24 h postoperatively. Conclusions: Intraoperative low-dose ketamine did not have a preemptive analgesic effect and was not effective as an adjuvant to decrease opioid requirement or postoperative pain score in parturients receiving intravenous PCA with fentanyl after caesarean section. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한통증학회 | - |
dc.title | The Effect of Low-dose Ketamine on Post-caesarean Delivery Analgesia after Spinal Anesthesia | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3344/kjp.2013.26.3.270 | - |
dc.identifier.scopusid | 2-s2.0-84880435908 | - |
dc.identifier.wosid | 000408949100007 | - |
dc.identifier.bibliographicCitation | The Korean Journal of Pain, v.26, no.3, pp 270 - 276 | - |
dc.citation.title | The Korean Journal of Pain | - |
dc.citation.volume | 26 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 270 | - |
dc.citation.endPage | 276 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001780728 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.subject.keywordAuthor | caesarean delivery | - |
dc.subject.keywordAuthor | ketamine | - |
dc.subject.keywordAuthor | patient-controlled analgesia | - |
dc.subject.keywordAuthor | preemptive analgesia | - |
dc.subject.keywordAuthor | spinal anesthesia | - |
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