Acute chorioamnionitis and intra-amniotic inflammation are more severe according to outside-in neutrophil migration within the same chorio-decidua
DC Field | Value | Language |
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dc.contributor.author | Oh, Jeong-Won | - |
dc.contributor.author | Moon, Kyung Chul | - |
dc.contributor.author | Park, Chan-Wook | - |
dc.contributor.author | Park, Joong Shin | - |
dc.contributor.author | Jun, Jong Kwan | - |
dc.date.accessioned | 2021-09-10T05:45:28Z | - |
dc.date.available | 2021-09-10T05:45:28Z | - |
dc.date.issued | 2021-07 | - |
dc.identifier.issn | 1028-4559 | - |
dc.identifier.issn | 1875-6263 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/18735 | - |
dc.description.abstract | Objective: No information exists about whether acute histologic chorioamnionitis (acute-HCA) is more advanced and severe, and intra-amniotic inflammation is more frequent and intense according to outside in neutrophil migration within the same chorio-decidua. The objective of current study is to examine this issue. Materials and methods: We included 106 singleton preterm-births (gestational age at delivery: 20-34 weeks) due to either preterm-labor or preterm-PROM in the context of acute chorio-deciduitis. Studypopulation was divided into 3 groups according to outside-in neutrophil migration within choriodecidua as follows: 1) group-1: 'inflammation restricted to the decidua' (n = 22); 2) group-2: 'inflammation restricted to the MT of chorion and the decidua' (n = 31); 3) group-3: 'inflammation in the CT of chorion' (n = 53). We examined the frequency of inflammation in each placental compartment beyond chorio-decidua (i.e., amnion, umbilical cord, and chorionic-plate), and total grade (1-8) of acute-HCA. Moreover, the frequency of intra-amniotic infection (defined as positive amniotic-fluid culture for aerobic and anaerobic bacteria and genital mycoplasmas) and intra-amniotic inflammation (defined as amniotic fluid WBC > 19 cells/mm3), and an intra-amniotic inflammatory response gauged by amnioticfluid WBC count (cells/mm3) were examined in 50 amniotic fluid samples within 7 days of birth. Results: Amnionitis, funisitis and chorionic plate inflammation were more frequent (each for P < 0.01) and median total grade of acute-HCA was increased (P < 0.001) according to outside-in neutrophil migration within chorio-decidua (group-1vs.group-2vs.group-3). Moreover, intra-amniotic infection and inflammation were more frequent (each-for P < 0.05) and median amniotic-fluid WBC count was increased (P < 0.01) according-to outside-in neutrophil-migration within chorio-decidua (group-1 vs. group-2 vs. group-3). Conclusion: Acute-HCA is more advanced and severe, and intra-amniotic inflammation is more frequent and intense according to outside in neutrophil migration within the same chorio-decidua. This finding suggests that what is now acute chorio-deciduitis should be subdivided. (c) 2021 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | - |
dc.format.extent | 14 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier Taiwan | - |
dc.title | Acute chorioamnionitis and intra-amniotic inflammation are more severe according to outside-in neutrophil migration within the same chorio-decidua | - |
dc.type | Article | - |
dc.publisher.location | 대만 | - |
dc.identifier.doi | 10.1016/j.tjog.2021.05.011 | - |
dc.identifier.scopusid | 2-s2.0-85107445510 | - |
dc.identifier.wosid | 000671884000011 | - |
dc.identifier.bibliographicCitation | Taiwanese Journal of Obstetrics and Gynecology, v.60, no.4, pp 639 - 652 | - |
dc.citation.title | Taiwanese Journal of Obstetrics and Gynecology | - |
dc.citation.volume | 60 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 639 | - |
dc.citation.endPage | 652 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.subject.keywordPlus | PRETERM PREMATURE RUPTURE | - |
dc.subject.keywordPlus | AMNIOTIC-FLUID INTERLEUKIN-6 | - |
dc.subject.keywordPlus | C-REACTIVE PROTEIN | - |
dc.subject.keywordPlus | BLOOD-CELL COUNT | - |
dc.subject.keywordPlus | HISTOLOGIC CHORIOAMNIONITIS | - |
dc.subject.keywordPlus | INTRAUTERINE INFECTION | - |
dc.subject.keywordPlus | FETAL | - |
dc.subject.keywordPlus | LESIONS | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | PLACENTAS | - |
dc.subject.keywordAuthor | Ascending intra-uterine infection | - |
dc.subject.keywordAuthor | Chorio-deciduitis | - |
dc.subject.keywordAuthor | Histologic chorio-amnionitis | - |
dc.subject.keywordAuthor | Intra-amniotic inflammation | - |
dc.subject.keywordAuthor | Neutrophil migration | - |
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