Comparison of the clinical characteristics of community-acquired acute pyelonephritis between male and female patients
- Authors
- Jang, Wooyoung; Jo, Hyun-uk; Kim, Bongyoung; Kwon, Ki Tae; Ryu, Seong-yeol; Wie, Seong-Heon; Kim, Jieun; Park, Se Yoon; Hong, Kyung-Wook; Kim, Hye In; Kim, Hyun Ah; Kim, Mi-Hee; Bae, Mi Hyun; Sohn, Yong-Hak; Kim, Jieun; Lee, Yangsoon; Pai, Hyunjoo
- Issue Date
- Jul-2021
- Publisher
- Elsevier Limited
- Keywords
- Pyelonephritis; Urinary tract infection; Male; Korea
- Citation
- Journal of Infection and Chemotherapy, v.27, no.7, pp 1013 - 1019
- Pages
- 7
- Journal Title
- Journal of Infection and Chemotherapy
- Volume
- 27
- Number
- 7
- Start Page
- 1013
- End Page
- 1019
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/18754
- DOI
- 10.1016/j.jiac.2021.02.014
- ISSN
- 1341-321X
1437-7780
- Abstract
- Background: Community-acquired acute pyelonephritis (CA-APN) is relatively rare in men. This study aimed to compare the clinical characteristics of CA-APN between male and female patients. Methods: We prospectively collected the clinical and microbiological data of hospitalized CA-APN patients aged 19 years in South Korea from March 2010 to February 2011 in 11 hospitals and from September 2017 to August 2018 in 8 hospitals. Only the first episodes of APN of each patient during the study period were included. Results: From 2010 to 2011, 573 patients from 11 hospitals were recruited, and from 2017 to 2018, 340 patients were recruited from 8 hospitals. Among them, 5.9% (54/913) were male. Male patients were older (66.0 +/- 15.2 vs. 55.3 +/- 19.0 years, P < 0.001), had a higher Charlson comorbidity index (1.3 +/- 1.5 vs. 0.7 +/- 1.2, P = 0.027), and had a higher proportion of structural problems in the urinary tract (40.7% vs. 6.1%, P < 0.001) than female patients. Moreover, the total duration of antibiotic treatment was longer (21.8 +/- 17.8 d vs. 17.3 +/- 9.4 d, P = 0.001) and the proportion of carbapenem usage was higher (24.1% vs. 9.5%, P = 0.001) in men than in women. Male patients were hospitalized for longer durations than female patients (median, 10 d vs. 7 d, P < 0.001). Conclusions: Male CA-APN patients were older and had more comorbidities than female CA-APN patients. In addition, male patients received antibiotic treatment for a longer duration than female patients. (c) 2021 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
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