Comparison of the 2017 EULAR/ACR Criteria with Clinicoserologic Criteria for the Classification of Idiopathic Inflammatory Myopathies in Korean Patients
DC Field | Value | Language |
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dc.contributor.author | Chung, Sang Wan | - |
dc.contributor.author | Yoo, In Seol | - |
dc.contributor.author | Kim, Jinhyun | - |
dc.contributor.author | Kang, Seong Wook | - |
dc.contributor.author | Kwon, Mihye | - |
dc.contributor.author | Joung, Chung-Il | - |
dc.contributor.author | Choi, In Ah | - |
dc.contributor.author | Chang, Sung Hae | - |
dc.contributor.author | Kang, Mi Il | - |
dc.contributor.author | Hong, Seung-Jae | - |
dc.contributor.author | Lee, Yeon-Ah | - |
dc.date.accessioned | 2021-09-10T05:48:34Z | - |
dc.date.available | 2021-09-10T05:48:34Z | - |
dc.date.issued | 2021-05 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.issn | 1976-2437 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/18865 | - |
dc.description.abstract | Purpose: To investigate correlations between myositis-specific autoantibodies (MSA) or myositis-associated antibodies (MAA) and clinical features, thereby demonstrating the utility of clinicoserologic classification in idiopathic inflammatory myopathies (IIM) patients. Materials and Methods: We conducted a multicenter study of 108 adult patients (age >= 18 years) who were diagnosed with IIM by Peter and Bohan criteria or 2004 European Neuromuscular Centre (ENMC) criteria. Clinical data were obtained by medical record review. Immunoblot assay with Euroline strip (EUROIMMUN, Germany) was performed using the sera of dermatomyositis (DM, n=56), polymyositis (PM, n=45), amyopathic DM (n=5), DM sine dermatitis (n=1), and immune mediated necrotizing myopathy (n=1) patients. Patients were classified based on two classifications: 2017 EULAR/ACR and novel clinicoserologic classification. Results: According to 2017 EULAR/ACR criteria, DM and PM were the most and the second most frequent entities. Overlap myositis was the major entity of IIM, and the frequency of PM was significantly lower when applying clinicoserologic classification criteria. Sixty-nine (63.9%) patients had one or more MSA, and 61 (56.5%) patients had one or more MAA. Interstitial lung disease was closely associated with anti-MDA5 and anti-ARS, and DM-specific skin lesions were frequently observed in patients with anti-TIF1 gamma, anti-SRP, and anti-MDA5. Conclusion: The clinicoserologic criteria based on MSA/MAA positivity could reflect more precise clinical features of IIM. Establishment of a laboratory system routinely available to screen for MSA/MAA status will be beneficial to provide precise diagnosis and proper management of IIM patients. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 연세대학교의과대학 | - |
dc.title | Comparison of the 2017 EULAR/ACR Criteria with Clinicoserologic Criteria for the Classification of Idiopathic Inflammatory Myopathies in Korean Patients | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3349/ymj.2021.62.5.424 | - |
dc.identifier.scopusid | 2-s2.0-85105896305 | - |
dc.identifier.wosid | 000649693300006 | - |
dc.identifier.bibliographicCitation | Yonsei Medical Journal, v.62, no.5, pp 424 - 430 | - |
dc.citation.title | Yonsei Medical Journal | - |
dc.citation.volume | 62 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 424 | - |
dc.citation.endPage | 430 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002707912 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | AUTOANTIBODIES | - |
dc.subject.keywordPlus | POLYMYOSITIS | - |
dc.subject.keywordPlus | MYOSITIS | - |
dc.subject.keywordPlus | OVERLAP | - |
dc.subject.keywordPlus | ADULT | - |
dc.subject.keywordAuthor | Idiopathic inflammatory myositis | - |
dc.subject.keywordAuthor | novel classification criteria | - |
dc.subject.keywordAuthor | overlap myositis | - |
dc.subject.keywordAuthor | myositis specific autoantibody | - |
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