Prognostic value of LI-RADS category on gadoxetic acid-enhanced MRI and 18F-FDG PET-CT in patients with primary liver carcinomas
DC Field | Value | Language |
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dc.contributor.author | Min, Ji Hye | - |
dc.contributor.author | Kim, Seong Hyun | - |
dc.contributor.author | Hwang, Jeong Ah | - |
dc.contributor.author | Hyun, Seung Hyup | - |
dc.contributor.author | Ha, Sang Yun | - |
dc.contributor.author | Choi, Seo-Youn | - |
dc.contributor.author | Kim, Seon Woo | - |
dc.contributor.author | Kim, Hye Seung | - |
dc.date.accessioned | 2021-09-10T06:27:40Z | - |
dc.date.available | 2021-09-10T06:27:40Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.issn | 1432-1084 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/19109 | - |
dc.description.abstract | Objectives To evaluate the postoperative prognostic value of the Liver Imaging Reporting and Data System (LI-RADS) category on gadoxetic acid-enhanced MRI and 18F-fluorodeoxyglucose PET-CT in patients with primary liver carcinomas (PLCs). Methods A total of 189 patients with chronic liver disease and surgically proven single PLC (42 intrahepatic cholangiocarcinomas and 21 combined hepatocellular-cholangiocarcinomas and 126 hepatocellular carcinomas [2:1 matching to non-HCC malignancies]) were retrospectively evaluated with gadoxetic acid-enhanced MRI and PET-CT. Two independent reviewers assigned an LI-RADS category for each observation. The tumor-to-liver standardized uptake value ratio (TLR) was calculated. The overall survival (OS), recurrence-free survival (RFS), and the associated factors were evaluated. Results In multivariable analysis, LI-RADS category (LR-4 or LR-5 [LR-4/5] vs. LR-M; OS, hazard ratio [HR] 2.24, p = 0.006; RFS, HR 1.61, p = 0.028) and TLR (low, < 2.3 vs. high, >= 2.3; OS, HR 2.09, p = 0.014; RFS, HR 2.17, p < 0.001) were the independent factors for OS and RFS. For the LR-M group, the high TLR group showed lower OS and RFS rates than the low TLR group (OS, p = 0.008; RFS, p < 0.001). For the LR-4/5 group, the OS and RFS rates were not significantly different between the high TLR and low TLR groups (both p > 0.05). Conclusions Both LI-RADS category on MRI and TLR on PET-CT are associated with the postoperative prognosis of PLCs. The prognosis of PLCs classified as LR-M can be further stratified according to the TLR group, but not for the PLCs classified as LR-4/5. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Prognostic value of LI-RADS category on gadoxetic acid-enhanced MRI and 18F-FDG PET-CT in patients with primary liver carcinomas | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s00330-020-07378-4 | - |
dc.identifier.scopusid | 2-s2.0-85096301500 | - |
dc.identifier.wosid | 000590962700008 | - |
dc.identifier.bibliographicCitation | European Radiology | - |
dc.citation.title | European Radiology | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | POSITRON-EMISSION-TOMOGRAPHY | - |
dc.subject.keywordPlus | COMBINED HEPATOCELLULAR-CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | INTRAHEPATIC CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | EARLY RECURRENCE | - |
dc.subject.keywordPlus | RESECTION | - |
dc.subject.keywordPlus | FEATURES | - |
dc.subject.keywordAuthor | Liver neoplasms | - |
dc.subject.keywordAuthor | Prognosis | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.subject.keywordAuthor | Positron emission tomography computed tomography | - |
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