Comparison of the prognostic values of F-18-fluorodeoxyglucose parameters from colon and non-colon sites of involvement in diffuse large B-cell lymphoma of the colon
DC Field | Value | Language |
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dc.contributor.author | Lim, Chae Hong | - |
dc.contributor.author | Hyun, Seung Hyup | - |
dc.contributor.author | Moon, Seung Hwan | - |
dc.contributor.author | Cho, Young Seok | - |
dc.contributor.author | Choi, Joon Young | - |
dc.contributor.author | Lee, Kyung-Han | - |
dc.date.accessioned | 2021-09-10T06:49:09Z | - |
dc.date.available | 2021-09-10T06:49:09Z | - |
dc.date.issued | 2020-07-29 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/19480 | - |
dc.description.abstract | We examined the prognostic values of F-18-fluorodeoxyglucose (F-18-FDG) parameters from colon, non-colon, and total lesions in patients with diffuse large B-cell lymphoma (DLBCL) of the colon. Positron emission tomography/computed tomography (PET/CT) in 50 patients was retrospectively analyzed for maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV) and total lesion glycolysis (TLG). During follow-up, 13 patients showed progression and 9 died from disease. Receiver operating characteristics (ROC) curve analysis showed that non-colon and total lesion MTV and TLG and colon lesion SUVmax were associated with progression or death. Significant univariate predictors of poor event-free survival (EFS) included stage III-IV, greater International Prognostic Index (IPI) score, no resection, high non-colon lesion SUVmax, MTV and TLG, and high total lesion MTV and TLG. Univariate predictors of poor overall survival (OS) included stage III-IV, greater IPI score, no resection, high non-colon lesion MTV and TLG, high total lesion MTV, and low colon lesion SUVmax. Multivariate analysis revealed that high non-colon lesion TLG was independently associated with poor EFS and OS. Low colon lesion SUVmax was also independently associated with poor OS. In a subgroup with colon-dominant involvement (n=35), non-colon lesion MTV and TLG were associated with events and non-colon lesion MTV was associated with patient death. Univariate analysis showed that high non-colon lesion MTV was a significant predictor of poor EFS and OS, while non-colon lesion TLG was a significant predictor of poor OS. Thus, volumetric FDG parameters of non-colon lesions offered significant prognostic information in patients with DLBCL of the colon. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Nature Publishing Group | - |
dc.title | Comparison of the prognostic values of F-18-fluorodeoxyglucose parameters from colon and non-colon sites of involvement in diffuse large B-cell lymphoma of the colon | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1038/s41598-020-69550-6 | - |
dc.identifier.scopusid | 2-s2.0-85088823584 | - |
dc.identifier.wosid | 000556388300002 | - |
dc.identifier.bibliographicCitation | Scientific Reports, v.10, no.1 | - |
dc.citation.title | Scientific Reports | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | POSITRON-EMISSION-TOMOGRAPHY | - |
dc.subject.keywordPlus | TOTAL LESION GLYCOLYSIS | - |
dc.subject.keywordPlus | METABOLIC TUMOR VOLUME | - |
dc.subject.keywordPlus | NON-HODGKINS-LYMPHOMAS | - |
dc.subject.keywordPlus | FDG-PET | - |
dc.subject.keywordPlus | BIOLOGICAL CHARACTERIZATION | - |
dc.subject.keywordPlus | F-18-FDG PET/CT | - |
dc.subject.keywordPlus | FREE SURVIVAL | - |
dc.subject.keywordPlus | LUNG-CANCER | - |
dc.subject.keywordPlus | PREDICTOR | - |
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