Ultrasonographic Changes of Major Salivary Glands in Primary Sjogren's Syndrome
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Kyung-Ann | - |
dc.contributor.author | Lee, Sang-Heon | - |
dc.contributor.author | Kim, Hae-Rim | - |
dc.date.accessioned | 2021-09-10T06:51:05Z | - |
dc.date.available | 2021-09-10T06:51:05Z | - |
dc.date.issued | 2020-03 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/19563 | - |
dc.description.abstract | We aimed to evaluate the changes over time in salivary gland (SG) abnormalities by ultrasound (US) in patients with primary Sjogren's syndrome (pSS). Patients with pSS (n = 70) and idiopathic sicca syndrome (n = 18) underwent baseline salivary gland ultrasound (SGUS) scans, and follow-up scans two years later. The semi-quantitative SGUS score (0-48) and intraglandular power Doppler signal (PDS) were assessed. We found that in the pSS group, the SGUS scores for total SGs and bilateral parotid glands significantly increased after the median 23.4-months follow-up. SGUS scores either worsened, improved, or were stable in 18.6%, 2.9%, and 78.6% of patients with pSS, respectively. The median changes from baseline in SGUS scores for total and parotid glands were +1.0 and +0.5, respectively. None of the SGUS scores changed significantly in the controls. The variables of homogeneity and hypoechoic showed a statistically significant progression of SGUS scores. In pSS patients, the baseline and follow-up PDS scores were significantly higher in the "worsening" group than in the "no change/improvement" group. Overall, the structural abnormalities in major SGs assessed using SGUS remained stable in patients with pSS. At the 2-year follow-up, SGUS scores worsened in 18.6% of patients with pSS. Intra-glandular hypervascularity was associated with the worsening of SG abnormalities. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI AG | - |
dc.title | Ultrasonographic Changes of Major Salivary Glands in Primary Sjogren's Syndrome | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/jcm9030803 | - |
dc.identifier.scopusid | 2-s2.0-85099969878 | - |
dc.identifier.wosid | 000527278800192 | - |
dc.identifier.bibliographicCitation | Journal of Clinical Medicine, v.9, no.3 | - |
dc.citation.title | Journal of Clinical Medicine | - |
dc.citation.volume | 9 | - |
dc.citation.number | 3 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | CLASSIFICATION CRITERIA | - |
dc.subject.keywordPlus | DIAGNOSTIC-VALUE | - |
dc.subject.keywordPlus | ULTRASOUND | - |
dc.subject.keywordPlus | CONSENSUS | - |
dc.subject.keywordPlus | FLOW | - |
dc.subject.keywordPlus | PROGRESSION | - |
dc.subject.keywordPlus | RITUXIMAB | - |
dc.subject.keywordPlus | LESIONS | - |
dc.subject.keywordPlus | SCORE | - |
dc.subject.keywordAuthor | Sjogren's syndrome | - |
dc.subject.keywordAuthor | salivary glands | - |
dc.subject.keywordAuthor | ultrasonography | - |
dc.subject.keywordAuthor | doppler | - |
dc.subject.keywordAuthor | longitudinal studies | - |
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