Adverse Events Associated With Peroral Endoscopic Myotomy Affecting Extended Hospital Stay: A Multi-center Retrospective Study in South Korea
- Authors
- Lee, Ju Yup; Lim, Chul-Hyun; Kim, Do Hoon; Jung, Hwoon-Yong; Youn, Young Hoon; Jung, Da Hyun; Park, Jun Chul; Moon, Hee Seok; Hong, Su Jin
- Issue Date
- 1-Apr-2022
- Publisher
- 대한소화기 기능성질환∙운동학회
- Keywords
- Achalasia; Adverse events; Endoscopic myotomy; Esophageal motility disorder; Hospital stay
- Citation
- Journal of Neurogastroenterology and Motility (JNM), v.28, no.2, pp 247 - 254
- Pages
- 8
- Journal Title
- Journal of Neurogastroenterology and Motility (JNM)
- Volume
- 28
- Number
- 2
- Start Page
- 247
- End Page
- 254
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/20682
- DOI
- 10.5056/jnm21081
- ISSN
- 2093-0879
2093-0887
- Abstract
- Background/Aims To analyze various adverse events (AEs) related to the peroral endoscopic myotomy (POEM) procedure and to analyze whether these AEs are related to an extended hospital stay. Methods Patients admitted for POEM for esophageal motility disorders from August 2012 to February 2020 at 5 centers were retrospectively collected. Length of hospital stay, AEs during or after the POEM procedure were analyzed. Results Of the 328 patients, 63.1% did not have any AEs, but 2.4% had major AEs, and 33.4% had minor AEs. Major AEs included mucosal injury, bleeding, and hemothorax, accounting for 1.5%, 0.6%, and 0.3%, respectively. Among the minor AEs, pneumoperitoneum was the most common gas-related AEs. Among non-gas-related minor AEs, pneumonia was the most common at 4.6%, followed by pain, fever, and pleural effusion. All major AEs had meaningful delayed discharge and significantly extended hospital stay compared to the no AEs group (median differences range 4.5-9.0 days). Among gas-related minor AEs, except for 4 cases of emphysema, the extended hospital stay was meaningless. All non-gas-related minor AEs was associated with a significant prolongation of hospital stay compared to that in the no AEs group (median differences range 2.0-4.0 days). Conclusions In conclusion, most gas-related minor AEs do not significantly affect the patient's clinical course. However, subcutaneous emphysema and minor non-gas related AEs such as pneumonia, pain, fever, and pleural effusion can prolong the hospital stay, therefore careful observation is required. Efforts will be made to reduce major AEs that significantly prolong hospitalization.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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