The efficacy of fractional carbon dioxide laser combined with narrow-band ultraviolet B phototherapy for non-segmental vitiligo: a systematic review and meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Kim, Woo Il | - |
dc.contributor.author | Kim, Sooyoung | - |
dc.contributor.author | Lee, Sang Hoon | - |
dc.contributor.author | Cho, Moon Kyun | - |
dc.date.accessioned | 2021-08-11T08:30:10Z | - |
dc.date.available | 2021-08-11T08:30:10Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 0268-8921 | - |
dc.identifier.issn | 1435-604X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2076 | - |
dc.description.abstract | Fractional carbon dioxide (CO2) laser has been used with conventional treatments for vitiligo, demonstrating more effectiveness compared with conventional treatments alone. Especially, fractional CO(2)laser combined with narrow-band ultraviolet B (NB-UVB) was shown to induce more improvement compared with NB-UVB monotherapy for treating stable non-segmental vitiligo. However, the effectiveness of fractional CO(2)laser plus NB-UVB for the treatment of non-segmental vitiligo remains controversial. Therefore, this study aimed to confirm the safety and efficacy of fractional CO(2)laser combined with NB-UVB compared with NB-UVB monotherapy in stable non-segmental vitiligo. We searched the data from different databases, including Cochrane, Embase, and PubMed up to January 2020. Four randomized controlled trials (RCTs) for comparison between fractional CO(2)laser plus NB-UVB and NB-UVB monotherapy in patients with stable non-segmental vitiligo were included. We performed meta-analyses for repigmentation improvement and patient satisfaction as well as subgroup analyses based on acral or non-acral vitiligo, according to the PRISMA guidelines. The combination treatment showed more superior results than NB-UVB monotherapy (>= 75% repigmentation, RR 4.60, 95% CI 1.19-17.74; >= 50% repigmentation, RR 2.24, 95% CI 0.45-11.17; < 25% repigmentation, RR 0.81, 95% CI 0.60-1.08). Also, fractional CO(2)laser plus NB-UVB significantly improved acral and non-acral vitiligo compared with NB-UVB monotherapy (standard mean difference (SMD) 1.24, 95% CI 0.66-1.82; SMD 1.14, 95% CI 0.67-1.60, respectively), while it increased markedly patient satisfaction compared with NB-UVB monotherapy (SMD 1.12, 95% CI 0.66-1.58). Collectively, this meta-analysis suggested that fractional CO(2)laser combined with NB-UVB might be more effective for treating non-segmental vitiligo than NB-UVB monotherapy. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | The efficacy of fractional carbon dioxide laser combined with narrow-band ultraviolet B phototherapy for non-segmental vitiligo: a systematic review and meta-analysis | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1007/s10103-020-03069-0 | - |
dc.identifier.scopusid | 2-s2.0-85086785430 | - |
dc.identifier.wosid | 000542078300001 | - |
dc.identifier.bibliographicCitation | Lasers in Medical Science, v.36, no.1, pp 165 - 173 | - |
dc.citation.title | Lasers in Medical Science | - |
dc.citation.volume | 36 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 165 | - |
dc.citation.endPage | 173 | - |
dc.type.docType | Review | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | RANDOMIZED HALF-BODY | - |
dc.subject.keywordPlus | NONSEGMENTAL VITILIGO | - |
dc.subject.keywordPlus | COMBINATION TREATMENT | - |
dc.subject.keywordPlus | TOPICAL STEROIDS | - |
dc.subject.keywordPlus | CO2-LASER | - |
dc.subject.keywordPlus | 5-FLUOROURACIL | - |
dc.subject.keywordPlus | DERMABRASION | - |
dc.subject.keywordPlus | MELANOCYTES | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordAuthor | Vitiligo | - |
dc.subject.keywordAuthor | Fractional carbon dioxide laser | - |
dc.subject.keywordAuthor | NB-UVB | - |
dc.subject.keywordAuthor | Meta-analysis | - |
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