Multisystem Inflammatory Syndrome in an Adult after COVID-19 Vaccination: a Case Report and Literature Reviewopen access
- Authors
- Park, Jung Wan; Yu, Shi Nae; Chang, Sung Hae; Ahn, Young Hyeon; Jeon, Min Hyok
- Issue Date
- Nov-2021
- Publisher
- 대한의학회
- Keywords
- Coronavirus Disease 2019 (COVID-19); COVID-19 Vaccination; Multisystem Inflammatory Syndrome; Methylprednisolone
- Citation
- Journal of Korean Medical Science, v.36, no.45, pp 1 - 7
- Pages
- 7
- Journal Title
- Journal of Korean Medical Science
- Volume
- 36
- Number
- 45
- Start Page
- 1
- End Page
- 7
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/20791
- DOI
- 10.3346/jkms.2021.36.e312
- ISSN
- 1011-8934
1598-6357
- Abstract
- As the number of people vaccinated increases, people who complain of adverse reactions continue to occur. We experienced a case characterized by low blood pressure, persistent fever, edema due to increased systemic vascular permeability, and systemic inflammation confirmed by image and laboratory examinations after ChAdOx1 coronavirus disease 2019 (COVID-19) vaccination. The diagnostic criteria for multisystem inflammatory syndrome (MIS) in adults are known as fever of 3 days or more in adults, 2 or more mucocutaneous/gastrointestinal/neurologic symptoms, elevation of inflammatory markers, and clinical/ imaging diagnosis of heart failure. A 67-year-old man who was medicated for hypertension and diabetes was admitted complaining of fever, maculopapular rash, diarrhea, headache, chills, and dizziness 6 days after the first vaccination of ChAdOx1 nCoV-19 in Korea. The COVID-19 test was negative but with low blood pressure, leukocytosis, skin rash, pulmonary edema, and increased inflammation markers. His lab findings and clinical course were consistent with those of MIS after COVID-19 vaccination. He was medicated with methylprednisolone 1 mg/kg and diuretics and recovered rapidly. He was discharged after 2 weeks and confirmed cure at outpatient clinic. We report an MIS case after COVID-19 vaccination in Korea.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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