Fatigue is associated with depression independent of excessive daytime sleepiness in the general population
DC Field | Value | Language |
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dc.contributor.author | Sunwoo, Jun-Sang | - |
dc.contributor.author | Kim, Daeyoung | - |
dc.contributor.author | Chu, Min Kyung | - |
dc.contributor.author | Yun, Chang-Ho | - |
dc.contributor.author | Yang, Kwang Ik | - |
dc.date.accessioned | 2022-06-09T02:49:48Z | - |
dc.date.available | 2022-06-09T02:49:48Z | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 1520-9512 | - |
dc.identifier.issn | 1522-1709 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/20989 | - |
dc.description.abstract | Purpose This study aimed to investigate sleep problems and comorbid conditions associated with fatigue in the general population. Methods The data were obtained from a nationwide cross-sectional survey conducted in 2018. The Fatigue Severity Scale was used to assess fatigue. We examined sleep habits, such as workday sleep duration, chronotype, and free-day catch-up sleep, excessive daytime sleepiness (EDS), depression, and other comorbid conditions. We conducted multiple logistic regression analysis with the presence of fatigue as a dependent variable. Results Of 2,493 adults aged 19 to 92 years, 50% men, mean age was 47.9 +/- 16.4 years. The average workday sleep duration was 7.1 +/- 1.1 h, and the prevalence of fatigue was 31%. After adjusting for potential confounders, fatigue was associated with EDS (odds ratio [OR] 3.751, 95% confidence interval [CI] 2.928-4.805), depression (OR 3.736, 95% CI 2.701-5.169), perceived insufficient sleep (OR 1.516, 95% CI 1.249-1.839), free-day catch-up sleep (OR 1.123, 95% CI 1.020-1.235), less alcohol intake (OR 0.570, 95% CI 0.432-0.752), and physical inactivity (OR 0.737, 95% CI 0.573-0.948). On subgroup analysis, fatigue was additionally associated with short workday sleep duration (OR 0.899, 95% CI 0.810-0.997) in individuals without EDS. However, among those with EDS, only depression (OR 2.842, 95% CI 1.511-5.343) and less alcohol intake (OR 0.476, 95% CI 0.247-0.915) were associated with fatigue. Conclusion Fatigue was significantly associated with depression independent of EDS. Further research is warranted to better understand the pathophysiological relationship between fatigue, depression, and sleep. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Thieme Medical Publishers | - |
dc.title | Fatigue is associated with depression independent of excessive daytime sleepiness in the general population | - |
dc.type | Article | - |
dc.publisher.location | 독일 | - |
dc.identifier.doi | 10.1007/s11325-021-02448-3 | - |
dc.identifier.scopusid | 2-s2.0-85110968245 | - |
dc.identifier.wosid | 000675734700001 | - |
dc.identifier.bibliographicCitation | Sleep and Breathing, v.26, no.2, pp 933 - 940 | - |
dc.citation.title | Sleep and Breathing | - |
dc.citation.volume | 26 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 933 | - |
dc.citation.endPage | 940 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | COMMUNITY | - |
dc.subject.keywordPlus | DURATION | - |
dc.subject.keywordPlus | COMPLAINTS | - |
dc.subject.keywordAuthor | Fatigue | - |
dc.subject.keywordAuthor | Sleepiness | - |
dc.subject.keywordAuthor | Depression | - |
dc.subject.keywordAuthor | Sleep duration | - |
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