Clinical Feasibility of Shear Wave Dispersion Slope for Noninvasive Diagnosis of Nonalcoholic Steatohepatitis in Patients With Morbid Obesity Preliminary Results Using US Shear Wave Elastography
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yeonsoo | - |
dc.contributor.author | Hwang, Jiyoung | - |
dc.contributor.author | Bae, Sung Hwan | - |
dc.contributor.author | Hong, Seong Sook | - |
dc.contributor.author | Chang, Yun-Woo | - |
dc.contributor.author | Kim, Hyun-joo | - |
dc.contributor.author | Kim, Sang Hyun | - |
dc.contributor.author | Jin, So-Young | - |
dc.date.accessioned | 2022-06-21T00:49:54Z | - |
dc.date.available | 2022-06-21T00:49:54Z | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 0894-8771 | - |
dc.identifier.issn | 1536-0253 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21063 | - |
dc.description.abstract | We aimed to investigate the clinical feasibility of shear wave dispersion slope for assessing nonalcoholic steatohepatitis (NASH) in patients with morbid obesity before bariatric surgery. This prospective study collected data from 25 participants who received liver biopsy during bariatric surgery between February 2019 and December 2020. All participants underwent ultrasonography shear wave elastography before surgery and shear wave speed and shear wave dispersion slope were measured. Liver specimens were evaluated by 1 pathologist scored histologically for nonalcoholic fatty liver disease (NAFLD). Ultrasonography measurements were compared according to histopathologic findings. Diagnostic performance in differentiating NASH from NAFLD was evaluated using the area under the receiver operating characteristic curve (AUC). Median shear wave speed (1.48 vs 1.62 m/s, P = 0.014) and dispersion slope (8.40 vs 11.80 [m/s]/kHz, P = 0.004) were higher in NASH group than in NAFLD group. Shear wave dispersion slope tended to increase step by step as the severity of activity grade (P = 0.032) and hepatic fibrosis (P = 0.015) increased. The AUC of shear wave dispersion slope for differentiating NASH from NAFLD (AUC, 0.83; 95% confidence intervals, 0.66-1.00) was higher than that of shear wave speed (AUC, 0.78; 95% CI, 0.60-0.97), although it did not reach statistical significance (P = 0.729). Shear wave dispersion slope could be a feasible tool for assessing NASH in patients with morbid obesity. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Clinical Feasibility of Shear Wave Dispersion Slope for Noninvasive Diagnosis of Nonalcoholic Steatohepatitis in Patients With Morbid Obesity Preliminary Results Using US Shear Wave Elastography | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1097/RUQ.0000000000000599 | - |
dc.identifier.scopusid | 2-s2.0-85131771270 | - |
dc.identifier.wosid | 000808202100008 | - |
dc.identifier.bibliographicCitation | Ultrasound Quarterly, v.38, no.2, pp 149 - 154 | - |
dc.citation.title | Ultrasound Quarterly | - |
dc.citation.volume | 38 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 149 | - |
dc.citation.endPage | 154 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | FATTY LIVER-DISEASE | - |
dc.subject.keywordPlus | ULTRASOUND ELASTOGRAPHY | - |
dc.subject.keywordPlus | FIBROSIS STAGE | - |
dc.subject.keywordPlus | SCORING SYSTEM | - |
dc.subject.keywordPlus | RECOMMENDATIONS | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | ELASTICITY | - |
dc.subject.keywordPlus | VISCOSITY | - |
dc.subject.keywordPlus | ALGORITHM | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordAuthor | nonalcoholic fatty liver disease | - |
dc.subject.keywordAuthor | ultrasonography | - |
dc.subject.keywordAuthor | elasticity imaging techniques | - |
dc.subject.keywordAuthor | morbid obesity | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.