Outcome of pallidal deep brain stimulation for treating isolated orofacial dystonia
DC Field | Value | Language |
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dc.contributor.author | Huh, Ryoong | - |
dc.contributor.author | Chung, Moonyoung | - |
dc.contributor.author | Jang, Il | - |
dc.date.accessioned | 2022-09-06T06:41:42Z | - |
dc.date.available | 2022-09-06T06:41:42Z | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 0001-6268 | - |
dc.identifier.issn | 0942-0940 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21360 | - |
dc.description.abstract | Background Isolated orofacial dystonia is a rare segmental neurological disorder that affects the eye, mouth, face, and jaws. Current literature on pallidal surgery for orofacial dystonia is limited to case reports and small-scale studies. This study was to investigate clinical outcomes of deep brain stimulation (DBS) of the globus pallidus internus (GPi) in patients with isolated orofacial dystonia. Methods Thirty-six patients who underwent GPi DBS at Incheon St. Mary's Hospital, The Catholic University of Korea, between 2014 and 2019 were included in this study. Burke-Fahn-Marsden Dystonia Rating Scale, Unified Dystonia Rating Scale, and Global Dystonia Severity Rating Scale were retrospectively retrieved for analysis before surgery, at 6-month follow-up as short-term outcome, and at follow-up over 1 year (12 months to 69 months) as long-term results. Results Mean total BFMDRS-M scores at the three time points (baseline, 6 months, and over 1 year follow-up) were 11.6 +/- 4.9, 6.1 +/- 5.2 (50.3 +/- 29.9% improvement, p < 0.05), and 4.3 +/- 4.2 (65.0 +/- 24.2% improvement, p < 0.05), respectively. In terms of UDRS and GDS, improvement rates were 45.1% (p < 0.001) and 47.7% (p < 0.001) at 6 months, and 63.8% (p < 0.001) and 65.7% (p < 0.001) at over 1 year after surgery, respectively. Conclusions Bilateral GPi DBS in isolated orofacial dystonia can be effective if conservative treatment option fails. Its benefit is not only observed in a short term, but also maintained in a long-term follow-up. | - |
dc.format.extent | 12 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Outcome of pallidal deep brain stimulation for treating isolated orofacial dystonia | - |
dc.type | Article | - |
dc.publisher.location | 오스트리아 | - |
dc.identifier.doi | 10.1007/s00701-022-05320-9 | - |
dc.identifier.scopusid | 2-s2.0-85137125562 | - |
dc.identifier.wosid | 000830922000001 | - |
dc.identifier.bibliographicCitation | Acta Neurochirurgica, v.164, no.9, pp 2287 - 2298 | - |
dc.citation.title | Acta Neurochirurgica | - |
dc.citation.volume | 164 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2287 | - |
dc.citation.endPage | 2298 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | MEIGE-SYNDROME | - |
dc.subject.keywordPlus | GLOBUS-PALLIDUS | - |
dc.subject.keywordPlus | STEREOTAXIC THALAMOTOMY | - |
dc.subject.keywordPlus | CRANIOCERVICAL DYSTONIA | - |
dc.subject.keywordPlus | GENERALIZED DYSTONIA | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | BLEPHAROSPASM | - |
dc.subject.keywordAuthor | Blepharospasm | - |
dc.subject.keywordAuthor | Meige syndrome | - |
dc.subject.keywordAuthor | Orofacial dystonia | - |
dc.subject.keywordAuthor | Oromandibular dystonia | - |
dc.subject.keywordAuthor | Deep brain stimulation | - |
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