A split-face study to evaluate the efficacy of a dissolving microneedle-encapsulated niacinamide skin patch for the reduction of facial hyperpigmentation
DC Field | Value | Language |
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dc.contributor.author | 배준석 | - |
dc.contributor.author | 남승민 | - |
dc.contributor.author | 차한규 | - |
dc.contributor.author | 박은수 | - |
dc.date.accessioned | 2022-11-28T08:40:54Z | - |
dc.date.available | 2022-11-28T08:40:54Z | - |
dc.date.created | 2022-11-28 | - |
dc.date.issued | 2022-10 | - |
dc.identifier.issn | 2234-0831 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21586 | - |
dc.description.abstract | ackground This study aimed to evaluate the efficacy and safety of a dissolving mi croneedle (DMN)-encapsulated niacinamide skin patch to reduce facial hyperpigmen tation. Methods A split-face study was conducted between April and June 2022 in 17 patients treated with a DMN-encapsulated niacinamide skin patch, which was applied only on the right side of the face, while the left face remained free of a pigmentation-improv ing agent. A topical moisturizer and physical sunscreen were applied on both sides of the face for 2 weeks. We compared both sides of the face 2 weeks after applying the skin patch using an automatic skin analysis device to investigate skin pigmentation. The melasma severity scores of both sides were evaluated before and 2 weeks after appli cation. Results A significant difference in the epidermal pigmentation score between pre treatment and 2 weeks after treatment was noted on the right side (P<0.05), but not on the left side of the face (P>0.05). A significant difference in the melanin score be tween pre-treatment and 2 weeks after treatment was noted on the right side (P<0.05), but not on the left side (P>0.05) of the face. There was no significant differ ence in the melasma severity score on either side of the face between pre-treatment and 2 weeks after treatment (P>0.05). Conclusions The application of a DMN-encapsulated niacinamide skin patch to improve skin pigmentation may yield good outcomes and provide comfort to patients without any complications. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한미용성형외과학회 | - |
dc.title | A split-face study to evaluate the efficacy of a dissolving microneedle-encapsulated niacinamide skin patch for the reduction of facial hyperpigmentation | - |
dc.title.alternative | A split-face study to evaluate the efficacy of a dissolving microneedle-encapsulated niacinamide skin patch for the reduction of facial hyperpigmentation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 배준석 | - |
dc.contributor.affiliatedAuthor | 남승민 | - |
dc.contributor.affiliatedAuthor | 차한규 | - |
dc.contributor.affiliatedAuthor | 박은수 | - |
dc.identifier.bibliographicCitation | Archives of Aesthetic Plastic Surgery, v.28, no.4, pp.113 - 118 | - |
dc.relation.isPartOf | Archives of Aesthetic Plastic Surgery | - |
dc.citation.title | Archives of Aesthetic Plastic Surgery | - |
dc.citation.volume | 28 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 113 | - |
dc.citation.endPage | 118 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002889427 | - |
dc.description.journalClass | 2 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Hyperpigmentation / Vitamin B3 / Skin | - |
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