Fabrication and characterization of cellulose nano crystal and soya modified injectable brushite bone cement for enhanced bone regeneration
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Tripathi, Garima | - |
dc.contributor.author | Park, Myeongki | - |
dc.contributor.author | Hossain, Mosharraf | - |
dc.contributor.author | Bin Im, Soo | - |
dc.contributor.author | Lee, Byong Taek | - |
dc.date.accessioned | 2022-11-29T04:40:19Z | - |
dc.date.available | 2022-11-29T04:40:19Z | - |
dc.date.issued | 2022-11 | - |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.issn | 1879-0003 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21720 | - |
dc.description.abstract | An inventive, cellulose nano crystal (CNC) and isolated soya flour (SPI) laden brushite-based injectable bone substitute (IBS) material has been developed in the present research. The purpose of the study was to discover the physical, mechanical, in-vitro biological, and in-vivo bone forming ability of the prepared IBS. The incomparable abilities of CNC together with SPI resulted in enhanced biocompatibility, mechanical strength, and biodegrad-ability, which together with its exclusive properties, sort it ideal for bone restoration. The CNC/SPI laden composites showed suitable mechanical strength of-10.5 MPa for BM23 composite. The in-vitro cytocompat-ibility of the prepared samples were evaluated by osteoblast type MC3T3-E1 cells via MTT assay. Protein ab-sorption and mineralization behavior of BRCNC2.0 was around (1.7 and 2.3)-fold higher than that of BR, respectively. In vivo performance was also found appreciable with-(31.33 +/- 2.04) % BV/TV. Incorporation of SPI resulted in enhanced bone formation at the central zone of the defect, while unmodified samples resulted in bone formation only at the peripheral zone. The findings of the current study proposed that CNC/SPI laden, brushite based injectable bone substitute might be proficient for bone regeneration ability. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | Fabrication and characterization of cellulose nano crystal and soya modified injectable brushite bone cement for enhanced bone regeneration | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.ijbiomac.2022.09.156 | - |
dc.identifier.scopusid | 2-s2.0-85138513114 | - |
dc.identifier.wosid | 000863559700003 | - |
dc.identifier.bibliographicCitation | International Journal of Biological Macromolecules, v.221, pp 1536 - 1544 | - |
dc.citation.title | International Journal of Biological Macromolecules | - |
dc.citation.volume | 221 | - |
dc.citation.startPage | 1536 | - |
dc.citation.endPage | 1544 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.subject.keywordPlus | PHOSPHATE CEMENTS | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordAuthor | 8-TCP | - |
dc.subject.keywordAuthor | Cellulose nano crystal | - |
dc.subject.keywordAuthor | Soya protein isolate | - |
dc.subject.keywordAuthor | Bone regeneration | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.