Epidemiological Trends of Pediatric Inflammatory Bowel Disease in Korea: A Multicenter Study of the Last 3 Years Including the COVID-19 Era br
DC Field | Value | Language |
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dc.contributor.author | Choi, So Yoon | - |
dc.contributor.author | Choi, Sujin | - |
dc.contributor.author | Kang, Ben | - |
dc.contributor.author | Choe, Byung-Ho | - |
dc.contributor.author | Lee, Yeoun Joo | - |
dc.contributor.author | Park, Jae Hong | - |
dc.contributor.author | Bin Kim, Yu | - |
dc.contributor.author | Kim, Jae Young | - |
dc.contributor.author | Lee, Kunsong | - |
dc.contributor.author | Lee, Kyung Jae | - |
dc.contributor.author | Kang, Ki Soo | - |
dc.contributor.author | Lee, Yoo Min | - |
dc.contributor.author | Kim, Hyun Jin | - |
dc.contributor.author | Kang, Yunkoo | - |
dc.contributor.author | Jang, Hyo-Jeong | - |
dc.contributor.author | Yi, Dae Yong | - |
dc.contributor.author | Hong, Suk Jin | - |
dc.contributor.author | Choi, You Jin | - |
dc.contributor.author | Hong, Jeana | - |
dc.contributor.author | Kim, Soon Chul | - |
dc.date.accessioned | 2022-11-29T05:42:05Z | - |
dc.date.available | 2022-11-29T05:42:05Z | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21806 | - |
dc.description.abstract | Background: Studies on how the coronavirus pandemic has affected pediatric inflammatory bowel disease (PIBD) are lacking. We aimed to investigate the trends in epidemiology, characteristics, initial management, and short-term outcomes of PIBD in South Korea over the recent three years including the era of coronavirus disease 2019 (COVID-19).Methods: This multicenter study retrospectively investigated temporal trends in the epidemiology of PIBD in Korea. Annual occurrences, disease phenotypes, and initial management at diagnosis were analyzed from January 2018 to June 2021.Results: A total of 486 patients from 17 institutions were included in this epidemiological evaluation. Analysis of the occurrence trend confirmed a significant increase in PIBD, regardless of the COVID-19 pandemic. In Crohn's disease, patients with post-coronavirus outbreaks had significantly higher fecal calprotectin levels than those with previous onset (1,339.4 +/- 717.04 vs. 1,595.5 +/- 703.94, P = 0.001). Patients with post-coronavirus-onset ulcerative colitis had significantly higher Pediatric Ulcerative Colitis Activity Index scores than those with previous outbreaks (48 +/- 17 vs. 36 +/- 15, P = 0.004). In the initial treatment of Crohn's disease, the use of 5-aminosalicylic acid (5-ASA) and steroids significantly decreased (P = 0.006 and 0.001, respectively), and enteral nutrition and the use of infliximab increased significantly (P = 0.045 and 0.009, respectively). There was a significant increase in azathioprine use during the initial treatment of ulcerative colitis (P = 0.020).Conclusion: Regardless of the COVID-19 pandemic, the number of patients with PIBD is increasing significantly annually in Korea. The initial management trends for PIBD have also changed. More research is needed to establish appropriate treatment guidelines considering the epidemiological and clinical characteristics of Korean PIBD. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한의학회 | - |
dc.title | Epidemiological Trends of Pediatric Inflammatory Bowel Disease in Korea: A Multicenter Study of the Last 3 Years Including the COVID-19 Era br | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3346/jkms.2022.37.e279 | - |
dc.identifier.scopusid | 2-s2.0-85138615882 | - |
dc.identifier.wosid | 000864465400005 | - |
dc.identifier.bibliographicCitation | Journal of Korean Medical Science, v.37, no.37 | - |
dc.citation.title | Journal of Korean Medical Science | - |
dc.citation.volume | 37 | - |
dc.citation.number | 37 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | ENDOSCOPIC ACTIVITY | - |
dc.subject.keywordPlus | CROHNS-DISEASE | - |
dc.subject.keywordPlus | VALIDATION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | INDEX | - |
dc.subject.keywordPlus | SCORE | - |
dc.subject.keywordAuthor | Inflammatory Bowel Disease | - |
dc.subject.keywordAuthor | Pediatric | - |
dc.subject.keywordAuthor | COVID-19 | - |
dc.subject.keywordAuthor | Occurrence | - |
dc.subject.keywordAuthor | Management | - |
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