Elevated blood viscosity is associated with delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage
DC Field | Value | Language |
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dc.contributor.author | Yi, Ho Jun | - |
dc.contributor.author | Shin, Dong-Seong | - |
dc.contributor.author | Kim, Bum -Tae | - |
dc.date.accessioned | 2022-11-29T06:40:36Z | - |
dc.date.available | 2022-11-29T06:40:36Z | - |
dc.date.issued | 2022-12 | - |
dc.identifier.issn | 1052-3057 | - |
dc.identifier.issn | 1532-8511 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21831 | - |
dc.description.abstract | Objectives: Delayed cerebral ischemia (DCI) is a contributing factor for poor clinical outcome in aneurysmal subarachnoid hemorrhage (aSAH). Blood viscosity can reflect flow resistance and dehydration status. Our study aimed to analyze the asso-ciation between blood viscosity and DCI in patients with aSAH. Methods: In this ret-rospective cohort, systolic blood viscosity (SBV) and diastolic blood viscosity (DBV) were measured at admission in patients with aSAH. Receiver operating characteris-tic curve analysis was used to assess the predictive values of SBV and DBV for DCI after aSAH. Univariate and multivariate logistic regression was performed to ana-lyze the association between blood viscosity and the development of DCI. Results: A total of 470 patients with aSAH were included in this study, and 184 (39.1%) patients had DCI. Optimal cut-off values of DBV and SBV were presented as 12.05 (cP) and 3.75 (cP), respectively. In addition, DBV has higher predictable value of DCI than SBV (DBV: area under the curve [AUC] 0.793; standard error [SE] 0.026; 95% CI 0.722-0.864; P < 0.001, and SBV: AUC 0.702; SE 0.040; 95% CI 0.624-0.781; P < 0.001). In multivariate logistic regression analysis, elevated DBV was a predicting factor for development of DCI (odds ratio: 1.60; 95% confidence interval: 1.32-2.58; P = 0.037). Conclusions: Blood viscosity is associated with development of DCI in patients with aSAH. Especially, DBV has a higher predictive value for the occurrence of DCI than SBV. Elevated DBV is a potential predicting factor for the occurrence of DCI. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | W. B. Saunders Co., Ltd. | - |
dc.title | Elevated blood viscosity is associated with delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.jstrokecerebrovasdis.2022.106732 | - |
dc.identifier.scopusid | 2-s2.0-85139343126 | - |
dc.identifier.wosid | 000878291000011 | - |
dc.identifier.bibliographicCitation | Journal of Stroke and Cerebrovascular Diseases, v.31, no.12 | - |
dc.citation.title | Journal of Stroke and Cerebrovascular Diseases | - |
dc.citation.volume | 31 | - |
dc.citation.number | 12 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | UREA NITROGEN/CREATININE RATIO | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | STROKE PATIENTS | - |
dc.subject.keywordPlus | VASOSPASM | - |
dc.subject.keywordPlus | PLASMA | - |
dc.subject.keywordPlus | MICROTHROMBOSIS | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | OCCLUSION | - |
dc.subject.keywordPlus | EVENT | - |
dc.subject.keywordAuthor | Aneurysm | - |
dc.subject.keywordAuthor | Blood viscosity | - |
dc.subject.keywordAuthor | Delayed cerebral ischemia | - |
dc.subject.keywordAuthor | Subarachnoid hemorrhage | - |
dc.subject.keywordAuthor | Vasospasm | - |
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