Gadoxetate disodium-enhanced MRI for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: late portal venous phase may improve identification of enhancing capsule
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyeji | - |
dc.contributor.author | Kim, Seung Soo | - |
dc.contributor.author | Shin, Hyeong Cheol | - |
dc.contributor.author | Choi, Seo-Youn | - |
dc.contributor.author | Lee, Ji Eun | - |
dc.contributor.author | Lee, Woong Hee | - |
dc.contributor.author | Park, Chan Ho | - |
dc.contributor.author | Lee, Hyoung Nam | - |
dc.contributor.author | Kim, Shin Young | - |
dc.contributor.author | 박혜림 | - |
dc.contributor.author | Heo, Nam Hun | - |
dc.date.accessioned | 2023-03-09T01:40:29Z | - |
dc.date.available | 2023-03-09T01:40:29Z | - |
dc.date.issued | 2023-02 | - |
dc.identifier.issn | 2366-004X | - |
dc.identifier.issn | 2366-0058 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21956 | - |
dc.description.abstract | Purpose To investigate added value of late portal venous phase (LPVP) for identification of enhancing capsule (EC) on gadoxetate disodium-enhanced MRI (GD-MRI) for diagnosing hepatocellular carcinoma (HCC) in patients with chronic liver disease (CLD). Methods This retrospective study comprised 116 high-risk patients with 128 pathologically proven HCCs who underwent GD-MRI including arterial phase, conventional portal venous phase (CPVP, 60 s), LPVP (mean, 104.4 +/- 6.7 s; range, 90-119 s), and transitional phase (TP, 3 min). Two independent radiologists assessed the presence of major HCC features, including EC on CPVP and/or TP (CPVP/TP) and EC on LPVP. The frequency of EC was compared on GD-MRI between with and without inclusion of LPVP. The radiologists assigned Liver Imaging Reporting and Data System (LI-RADS) v2018 categories before and after identifying EC on LPVP. Results Of the total 128 HCCs, 74 and 73 revealed EC on CPVP/TP for reviewer 1 and 2, respectively. After inclusion of LPVP, each reviewer identified seven more EC [Reviewer 1, 57.8% (74/128) vs. 63.3% (81/128); Reviewer 2, 57.0% (73/128) vs. 62.5% (80/128); P = 0.016, respectively]. Sensitivities of LR-5 assignment for diagnosing HCCs were not significantly different in GD-MRI with or without LPVP for EC identification [Reviewer 1, 71.9% (92/128) vs. 72.7% (93/128); Reviewer 2, 75.0% (96/128) vs. 75.8% (97/128); P= 1.000, respectively]. Conclusion Including the LPVP in GD-MRI may improve identification of EC of HCC in patients with CLD. However, LI-RADS v2018 using GD-MRI showed comparable sensitivity for diagnosing HCC regardless of applying LPVP for EC. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer New York | - |
dc.title | Gadoxetate disodium-enhanced MRI for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: late portal venous phase may improve identification of enhancing capsule | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s00261-022-03756-2 | - |
dc.identifier.scopusid | 2-s2.0-85143503483 | - |
dc.identifier.wosid | 000898120200001 | - |
dc.identifier.bibliographicCitation | Abdominal Radiology | - |
dc.citation.title | Abdominal Radiology | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | LI-RADS | - |
dc.subject.keywordPlus | INTRAHEPATIC CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | HEPATOBILIARY AGENTS | - |
dc.subject.keywordPlus | EXTRACELLULAR AGENTS | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | FEATURES | - |
dc.subject.keywordPlus | CATEGORIZATION | - |
dc.subject.keywordPlus | PSEUDOCAPSULE | - |
dc.subject.keywordPlus | IMAGES | - |
dc.subject.keywordAuthor | Hepatocellular carcinoma | - |
dc.subject.keywordAuthor | Liver neoplasm | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.subject.keywordAuthor | Gadoxetate disodium | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.