Comparison of clinical characteristics and outcomes after surgery of gastric and small bowel GIST in single center experiences
DC Field | Value | Language |
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dc.contributor.author | Park, Nahyeon | - |
dc.contributor.author | Lim, Dae Ro | - |
dc.contributor.author | Kuk, Jung Cheol | - |
dc.contributor.author | Shin, Eung Jin | - |
dc.date.accessioned | 2023-03-09T07:40:31Z | - |
dc.date.available | 2023-03-09T07:40:31Z | - |
dc.date.issued | 2023-10 | - |
dc.identifier.issn | 1015-9584 | - |
dc.identifier.issn | 0219-3108 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/22151 | - |
dc.description.abstract | Objective Gastrointestinal stromal tumor (GIST) is a rare kind of neoplasm at the gastrointestinal tract. There are few studies regarding the comparison of gastric and small bowel GIST in Korea. We aimed to analyze clinical characteristics and outcomes between gastric and small bowel GIST after curative resection.Methods Between May 2005 and Dec 2017, 165 patients who underwent curative resection for gastric GIST (n = 115) and small bowel GIST (n = 50) were retrieved from a retrospective database. They were compared with respect to clinical, pathologic and oncological outcomes.Results The mean age at surgery in both two group was similar (58.8 vs. 58.6, p = 0.772). The rate of emergency admission and surgery was higher in small bowel GIST group (p < 0.005). The mitotic rate and risk category were not significantly different between the two groups. However, the T stage was higher in small bowel GIST compared to the T stage of gastric GIST (22.6% vs. 44.0%, p = 0.025). During the follow-up, 5-year disease free survival rate was worse in small bowel GIST (82.0%) compared gastric GIST (93.7%) (p = 0.032). 5-year survival rate was not significantly different between the two groups (100.0% vs. 97.7%, p = 0.578). The T stage, mitotic count, and risk category were independent prognostic factors for disease free survival of Gastric and small bowel GIST in Cox multivariate analysis.Conclusion Small bowel GIST has more advanced T stage and higher rate of emergency surgery. Disease free survival rate was worse in small bowel GIST. Larger scaled prospective study of small bowel GIST is needed. | - |
dc.format.extent | 5 | - |
dc.publisher | Elsevier Taiwan | - |
dc.title | Comparison of clinical characteristics and outcomes after surgery of gastric and small bowel GIST in single center experiences | - |
dc.type | Article | - |
dc.publisher.location | 싱가폴 | - |
dc.identifier.doi | 10.1016/j.asjsur.2022.12.114 | - |
dc.identifier.scopusid | 2-s2.0-85146331714 | - |
dc.identifier.wosid | 001091938600001 | - |
dc.identifier.bibliographicCitation | Asian Journal of Surgery, v.46, no.10, pp 4235 - 4239 | - |
dc.citation.title | Asian Journal of Surgery | - |
dc.citation.volume | 46 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 4235 | - |
dc.citation.endPage | 4239 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | GASTROINTESTINAL STROMAL TUMORS | - |
dc.subject.keywordPlus | INTERSTITIAL-CELLS | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | FEATURES | - |
dc.subject.keywordPlus | ERA | - |
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