Development of nanoclay-based nanocomposite surfaces with antibacterial properties for potential biomedical applications
DC Field | Value | Language |
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dc.contributor.author | Levana, Odelia | - |
dc.contributor.author | Jeong, Ji Hoon | - |
dc.contributor.author | Hur, Sung Sik | - |
dc.contributor.author | Seo, Wonbin | - |
dc.contributor.author | Lee, Minho | - |
dc.contributor.author | Noh, Kyung Mu | - |
dc.contributor.author | Hong, Soonkook | - |
dc.contributor.author | Park, Jae Hong | - |
dc.contributor.author | Lee, Ju Hun | - |
dc.contributor.author | Choi, Chulmin | - |
dc.contributor.author | Hwang, Yongsung | - |
dc.date.accessioned | 2023-04-28T08:40:03Z | - |
dc.date.available | 2023-04-28T08:40:03Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 1226-086X | - |
dc.identifier.issn | 1876-794X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/22387 | - |
dc.description.abstract | Biofilm formation on biomedical implant surfaces requires bacterial adhesion, which increases the risk of infection and chronic inflammation. Since intercalation of quaternary ammonium salts (QAS) into mont-morillonite (MMT) clay, known as organoclays, has been reported to increase surface broad-spectrum antibacterial properties, we aimed to develop an antibacterial surface composed of thermoplastic poly-urethane (TPU) embedded with bentonite and MMT clay containing QAS to prevent initial bacterial attachment. We evaluated its potential application in reducing bacterial adhesion and enhancing bacteria-killing properties using Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. Our results demonstrated that the nanoclay-embedded TPU surfaces with QAS significantly reduced the adhesion of E. coli and S. aureus by 68.82% and 65.18%, respectively, compared to the plain TPU surfaces. Additionally, a higher nanoclay concentration coating on the surface could enhance its effectiveness, as shown by 85.34% and 82.74% reduction in E. coli and S. aureus adhesion and killing efficiency. Furthermore, we observed that nanoclay-embedded TPU surfaces had no detrimental effects on the via-bility of human dermal fibroblasts. Taken together, these techniques could provide novel strategies for inhibiting bacterial adhesion and supporting bacteria killing on biomedical implant surfaces, as the inves-tigated surfaces are simple to synthesize, efficient, and cost-effective. (c) 2023 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved. | - |
dc.format.extent | 12 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국공업화학회 | - |
dc.title | Development of nanoclay-based nanocomposite surfaces with antibacterial properties for potential biomedical applications | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.1016/j.jiec.2022.12.052 | - |
dc.identifier.scopusid | 2-s2.0-85146064447 | - |
dc.identifier.wosid | 000944183700001 | - |
dc.identifier.bibliographicCitation | Journal of Industrial and Engineering Chemistry, v.120, pp 448 - 459 | - |
dc.citation.title | Journal of Industrial and Engineering Chemistry | - |
dc.citation.volume | 120 | - |
dc.citation.startPage | 448 | - |
dc.citation.endPage | 459 | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.subject.keywordPlus | POLYURETHANE NANOCOMPOSITES | - |
dc.subject.keywordPlus | BENTONITE | - |
dc.subject.keywordPlus | CLAY | - |
dc.subject.keywordPlus | MONTMORILLONITE | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | ADSORPTION | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | FTIR | - |
dc.subject.keywordAuthor | Antibacterial surface | - |
dc.subject.keywordAuthor | Montmorillonite | - |
dc.subject.keywordAuthor | Bentonite | - |
dc.subject.keywordAuthor | Quaternary ammonium salts | - |
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